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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.
Wray NR, Ripke S, Mattheisen M, Trzaskowski M, Byrne EM, Abdellaoui A, Adams MJ, Agerbo E, Air TM, Andlauer TMF, Bacanu SA, Bækvad-Hansen M, Beekman AFT, Bigdeli TB, Binder EB, Blackwood DRH, Bryois J, Buttenschøn HN, Bybjerg-Grauholm J, Cai N, Castelao E, Christensen JH, Clarke TK, Coleman JIR, Colodro-Conde L, Couvy-Duchesne B, Craddock N, Crawford GE, Crowley CA, Dashti HS, Davies G, Deary IJ, Degenhardt F, Derks EM, Direk N, Dolan CV, Dunn EC, Eley TC, Eriksson N, Escott-Price V, Kiadeh FHF, Finucane HK, Forstner AJ, Frank J, Gaspar HA, Gill M, Giusti-Rodríguez P, Goes FS, Gordon SD, Grove J, Hall LS, Hannon E, Hansen CS, Hansen TF, Herms S, Hickie IB, Hoffmann P, Homuth G, Horn C, Hottenga JJ, Hougaard DM, Hu M, Hyde CL, Ising M, Jansen R, Jin F, Jorgenson E, Knowles JA, Kohane IS, Kraft J, Kretzschmar WW, Krogh J, Kutalik Z, Lane JM, Li Y, Li Y, Lind PA, Liu X, Lu L, MacIntyre DJ, MacKinnon DF, Maier RM, Maier W, Marchini J, Mbarek H, McGrath P, McGuffin P, Medland SE, Mehta D, Middeldorp CM, Mihailov E, Milaneschi Y, Milani L, Mill J, Mondimore FM, Montgomery GW, Mostafavi S, Mullins N, Nauck M, Ng B, Nivard MG, Nyholt DR, O'Reilly PF, Oskarsson H, Owen MJ, Painter J… See abstract for full author list ➔ Wray NR, et al. Among authors: buttenschon hn. Nat Genet. 2018 May;50(5):668-681. doi: 10.1038/s41588-018-0090-3. Epub 2018 Apr 26. Nat Genet. 2018. PMID: 29700475 Free PMC article.
Functional variants of TSPAN8 are associated with bipolar disorder and schizophrenia.
Scholz CJ, Jacob CP, Buttenschon HN, Kittel-Schneider S, Boreatti-Hümmer A, Zimmer M, Walter U, Lesch KP, Mors O, Kneitz S, Deckert J, Reif A. Scholz CJ, et al. Among authors: buttenschon hn. Am J Med Genet B Neuropsychiatr Genet. 2010 Jun 5;153B(4):967-72. doi: 10.1002/ajmg.b.31057. Am J Med Genet B Neuropsychiatr Genet. 2010. PMID: 20052686
Support for a bipolar affective disorder susceptibility locus on chromosome 12q24.3.
Buttenschøn HN, Foldager L, Flint TJ, Olsen IM, Deleuran T, Nyegaard M, Hansen MM, Kallunki P, Christensen KV, Blackwood DH, Muir WJ, Straarup SE, Als TD, Nordentoft M, Børglum AD, Mors O. Buttenschøn HN, et al. Psychiatr Genet. 2010 Jun;20(3):93-101. doi: 10.1097/YPG.0b013e32833a2066. Psychiatr Genet. 2010. PMID: 20410851
Cross-disorder analysis of bipolar risk genes: further evidence of DGKH as a risk gene for bipolar disorder, but also unipolar depression and adult ADHD.
Weber H, Kittel-Schneider S, Gessner A, Domschke K, Neuner M, Jacob CP, Buttenschon HN, Boreatti-Hümmer A, Volkert J, Herterich S, Baune BT, Gross-Lesch S, Kopf J, Kreiker S, Nguyen TT, Weissflog L, Arolt V, Mors O, Deckert J, Lesch KP, Reif A. Weber H, et al. Among authors: buttenschon hn. Neuropsychopharmacology. 2011 Sep;36(10):2076-85. doi: 10.1038/npp.2011.98. Epub 2011 Jun 8. Neuropsychopharmacology. 2011. PMID: 21654738 Free PMC article.
A genome-wide study of panic disorder suggests the amiloride-sensitive cation channel 1 as a candidate gene.
Gregersen N, Dahl HA, Buttenschøn HN, Nyegaard M, Hedemand A, Als TD, Wang AG, Joensen S, Woldbye DP, Koefoed P, Kristensen AS, Kruse TA, Børglum AD, Mors O. Gregersen N, et al. Among authors: buttenschon hn. Eur J Hum Genet. 2012 Jan;20(1):84-90. doi: 10.1038/ejhg.2011.148. Epub 2011 Aug 3. Eur J Hum Genet. 2012. PMID: 21811305 Free PMC article.
Association of GRIN1 and GRIN2A-D with schizophrenia and genetic interaction with maternal herpes simplex virus-2 infection affecting disease risk.
Demontis D, Nyegaard M, Buttenschøn HN, Hedemand A, Pedersen CB, Grove J, Flint TJ, Nordentoft M, Werge T, Hougaard DM, Sørensen KM, Yolken RH, Mors O, Børglum AD, Mortensen PB. Demontis D, et al. Among authors: buttenschon hn. Am J Med Genet B Neuropsychiatr Genet. 2011 Dec;156B(8):913-22. doi: 10.1002/ajmg.b.31234. Epub 2011 Sep 14. Am J Med Genet B Neuropsychiatr Genet. 2011. PMID: 21919190
Depression, the Val66Met polymorphism, age, and gender influence the serum BDNF level.
Elfving B, Buttenschøn HN, Foldager L, Poulsen PH, Andersen JH, Grynderup MB, Hansen ÅM, Kolstad HA, Kaerlev L, Mikkelsen S, Thomsen JF, Børglum AD, Wegener G, Mors O. Elfving B, et al. Among authors: buttenschon hn. J Psychiatr Res. 2012 Sep;46(9):1118-25. doi: 10.1016/j.jpsychires.2012.05.003. Epub 2012 Jun 6. J Psychiatr Res. 2012. PMID: 22682508
72 results