Bussiere JL - Search Results

1

Biological Characterization of a Stable Effector Functionless (SEFL) Monoclonal Antibody Scaffold in Vitro.

Liu L, Jacobsen FW, Everds N, Zhuang Y, Yu YB, Li N, Clark D, Nguyen MP, Fort M, Narayanan P, Kim K, Stevenson R, Narhi L, Gunasekaran K, Bussiere JL. Liu L, et al. Among authors: bussiere jl. J Biol Chem. 2017 Feb 3;292(5):1876-1883. doi: 10.1074/jbc.M116.748707. Epub 2016 Dec 19. J Biol Chem. 2017. PMID: 27994063 Free PMC article.

2

A novel statistical algorithm for gene expression analysis helps differentiate pregnane X receptor-dependent and independent mechanisms of toxicity.

Mongan MA, Dunn RT, Vonderfecht S, Everds N, Chen G, Su C, Higgins-Garn M, Chen Y, Afshari CA, Williamson TL, Carlock L, Dipalma C, Moss S, Bussiere J, Qualls C, He YD, Hamadeh HK. Mongan MA, et al. PLoS One. 2010 Dec 21;5(12):e15595. doi: 10.1371/journal.pone.0015595. PLoS One. 2010. PMID: 21203578 Free PMC article.

3

An inter-laboratory retrospective analysis of immunotoxicological endpoints in non-human primates: flow cytometry immunophenotyping.

Krejsa CM, Neradilek MB, Polissar NL, Cox N, Clark D, Cowan L, Bussiere J, Lebrec H. Krejsa CM, et al. J Immunotoxicol. 2013 Oct-Dec;10(4):361-72. doi: 10.3109/1547691X.2012.755237. Epub 2013 Feb 6. J Immunotoxicol. 2013. PMID: 23384295 Review.

4

Placental transfer of a fully human IgG2 monoclonal antibody in the cynomolgus monkey, rat, and rabbit: a comparative assessment from during organogenesis to late gestation.

Moffat GJ, Retter MW, Kwon G, Loomis M, Hock MB, Hall C, Bussiere J, Lewis EM, Chellman GJ. Moffat GJ, et al. Birth Defects Res B Dev Reprod Toxicol. 2014 Apr;101(2):178-88. doi: 10.1002/bdrb.21105. Birth Defects Res B Dev Reprod Toxicol. 2014. PMID: 24753333

5

Nonclinical safety evaluation of erenumab, a CGRP receptor inhibitor for the prevention of migraine.

Bussiere JL, Davies R, Dean C, Xu C, Kim KH, Vargas HM, Chellman GJ, Balasubramanian G, Rubio-Beltran E, MaassenVanDenBrink A, Monticello TM. Bussiere JL, et al. Regul Toxicol Pharmacol. 2019 Aug;106:224-238. doi: 10.1016/j.yrtph.2019.05.013. Epub 2019 May 11. Regul Toxicol Pharmacol. 2019. PMID: 31085251 Free article. Review.

6

Infant cynomolgus monkeys exposed to denosumab in utero exhibit an osteoclast-poor osteopetrotic-like skeletal phenotype at birth and in the early postnatal period.

Boyce RW, Varela A, Chouinard L, Bussiere JL, Chellman GJ, Ominsky MS, Pyrah IT. Boyce RW, et al. Among authors: bussiere jl. Bone. 2014 Jul;64:314-25. doi: 10.1016/j.bone.2014.04.002. Epub 2014 Apr 13. Bone. 2014. PMID: 24727159

7

Polyethylene glycol modified FGF21 engineered to maximize potency and minimize vacuole formation.

Xu J, Bussiere J, Yie J, Sickmier A, An P, Belouski E, Stanislaus S, Walker KW. Xu J, et al. Bioconjug Chem. 2013 Jun 19;24(6):915-25. doi: 10.1021/bc300603k. Epub 2013 May 9. Bioconjug Chem. 2013. PMID: 23594041

8

Assessment of menstrual cycle length in cynomolgus monkeys as a female fertility endpoint of a biopharmaceutical in a 6 month toxicity study.

Bussiere JL, Moffat G, Zhou L, Tarlo KS. Bussiere JL, et al. Regul Toxicol Pharmacol. 2013 Aug;66(3):269-78. doi: 10.1016/j.yrtph.2013.05.002. Epub 2013 May 13. Regul Toxicol Pharmacol. 2013. PMID: 23680404

9

Reproductive toxicity of denosumab in cynomolgus monkeys.

Bussiere JL, Pyrah I, Boyce R, Branstetter D, Loomis M, Andrews-Cleavenger D, Farman C, Elliott G, Chellman G. Bussiere JL, et al. Reprod Toxicol. 2013 Dec;42:27-40. doi: 10.1016/j.reprotox.2013.07.018. Epub 2013 Jul 22. Reprod Toxicol. 2013. PMID: 23886817

10

Phosphatidylinositol 3-Kinase δ Inhibitor-Induced Immunomodulation and Secondary Opportunistic Infection in the Cynomolgus Monkey (Macaca fascicularis).

Werner JA, Ishida K, Wisler J, Karbowski C, Kalanzi J, Bussiere J, Monticello TM. Werner JA, et al. Toxicol Pathol. 2020 Dec;48(8):949-964. doi: 10.1177/0192623320966238. Epub 2020 Nov 28. Toxicol Pathol. 2020. PMID: 33252030

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