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Linezolid Concentrations in Plasma and Subcutaneous Tissue are Reduced in Obese Patients, Resulting in a Higher Risk of Underdosing in Critically Ill Patients: A Controlled Clinical Pharmacokinetic Study.
Simon P, Busse D, Petroff D, Dorn C, Ehmann L, Hochstädt S, Girrbach F, Dietrich A, Zeitlinger M, Kees F, Kloft C, Wrigge H. Simon P, et al. Among authors: busse d. J Clin Med. 2020 Apr 9;9(4):1067. doi: 10.3390/jcm9041067. J Clin Med. 2020. PMID: 32283731 Free PMC article.
Comparative Plasma and Interstitial Tissue Fluid Pharmacokinetics of Meropenem Demonstrate the Need for Increasing Dose and Infusion Duration in Obese and Non-obese Patients.
Busse D, Simon P, Schmitt L, Petroff D, Dorn C, Dietrich A, Zeitlinger M, Huisinga W, Michelet R, Wrigge H, Kloft C. Busse D, et al. Clin Pharmacokinet. 2022 May;61(5):655-672. doi: 10.1007/s40262-021-01070-6. Epub 2021 Dec 11. Clin Pharmacokinet. 2022. PMID: 34894344 Free PMC article. Clinical Trial.
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