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Selective ferroptosis vulnerability due to familial Alzheimer's disease presenilin mutations.
Greenough MA, Lane DJR, Balez R, Anastacio HTD, Zeng Z, Ganio K, McDevitt CA, Acevedo K, Belaidi AA, Koistinaho J, Ooi L, Ayton S, Bush AI. Greenough MA, et al. Among authors: bush ai. Cell Death Differ. 2022 Nov;29(11):2123-2136. doi: 10.1038/s41418-022-01003-1. Epub 2022 Apr 21. Cell Death Differ. 2022. PMID: 35449212 Free PMC article.
Tau protein: relevance to Parkinson's disease.
Lei P, Ayton S, Finkelstein DI, Adlard PA, Masters CL, Bush AI. Lei P, et al. Among authors: bush ai. Int J Biochem Cell Biol. 2010 Nov;42(11):1775-8. doi: 10.1016/j.biocel.2010.07.016. Epub 2010 Aug 1. Int J Biochem Cell Biol. 2010. PMID: 20678581 Review.
Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease.
Duce JA, Tsatsanis A, Cater MA, James SA, Robb E, Wikhe K, Leong SL, Perez K, Johanssen T, Greenough MA, Cho HH, Galatis D, Moir RD, Masters CL, McLean C, Tanzi RE, Cappai R, Barnham KJ, Ciccotosto GD, Rogers JT, Bush AI. Duce JA, et al. Among authors: bush ai. Cell. 2010 Sep 17;142(6):857-67. doi: 10.1016/j.cell.2010.08.014. Cell. 2010. PMID: 20817278 Free PMC article.
Copper promotes the trafficking of the amyloid precursor protein.
Acevedo KM, Hung YH, Dalziel AH, Li QX, Laughton K, Wikhe K, Rembach A, Roberts B, Masters CL, Bush AI, Camakaris J. Acevedo KM, et al. Among authors: bush ai. J Biol Chem. 2011 Mar 11;286(10):8252-8262. doi: 10.1074/jbc.M110.128512. Epub 2010 Dec 22. J Biol Chem. 2011. PMID: 21177866 Free PMC article.
GSK-3 in Neurodegenerative Diseases.
Lei P, Ayton S, Bush AI, Adlard PA. Lei P, et al. Among authors: bush ai. Int J Alzheimers Dis. 2011;2011:189246. doi: 10.4061/2011/189246. Epub 2011 May 4. Int J Alzheimers Dis. 2011. PMID: 21629738 Free PMC article.
The Alzheimer's therapeutic PBT2 promotes amyloid-β degradation and GSK3 phosphorylation via a metal chaperone activity.
Crouch PJ, Savva MS, Hung LW, Donnelly PS, Mot AI, Parker SJ, Greenough MA, Volitakis I, Adlard PA, Cherny RA, Masters CL, Bush AI, Barnham KJ, White AR. Crouch PJ, et al. Among authors: bush ai. J Neurochem. 2011 Oct;119(1):220-30. doi: 10.1111/j.1471-4159.2011.07402.x. Epub 2011 Aug 25. J Neurochem. 2011. PMID: 21797865 Free article.
489 results