Busciglio J - Search Results

1

Suppressing Aneuploidy-Associated Phenotypes Improves the Fitness of Trisomy 21 Cells.

Hwang S, Williams JF, Kneissig M, Lioudyno M, Rivera I, Helguera P, Busciglio J, Storchova Z, King MC, Torres EM. Hwang S, et al. Among authors: busciglio j. Cell Rep. 2019 Nov 19;29(8):2473-2488.e5. doi: 10.1016/j.celrep.2019.10.059. Cell Rep. 2019. PMID: 31747614 Free PMC article.

2

Adaptive downregulation of mitochondrial function in down syndrome.

Helguera P, Seiglie J, Rodriguez J, Hanna M, Helguera G, Busciglio J. Helguera P, et al. Among authors: busciglio j. Cell Metab. 2013 Jan 8;17(1):132-40. doi: 10.1016/j.cmet.2012.12.005. Cell Metab. 2013. PMID: 23312288 Free PMC article.

3

A role for thrombospondin-1 deficits in astrocyte-mediated spine and synaptic pathology in Down's syndrome.

Garcia O, Torres M, Helguera P, Coskun P, Busciglio J. Garcia O, et al. Among authors: busciglio j. PLoS One. 2010 Dec 2;5(12):e14200. doi: 10.1371/journal.pone.0014200. PLoS One. 2010. PMID: 21152035 Free PMC article.

4

ets-2 promotes the activation of a mitochondrial death pathway in Down's syndrome neurons.

Helguera P, Pelsman A, Pigino G, Wolvetang E, Head E, Busciglio J. Helguera P, et al. Among authors: busciglio j. J Neurosci. 2005 Mar 2;25(9):2295-303. doi: 10.1523/JNEUROSCI.5107-04.2005. J Neurosci. 2005. PMID: 15745955 Free PMC article.

5

Cryopreservation of cortical tissue blocks for the generation of highly enriched neuronal cultures.

Rahman AS, Parvinjah S, Hanna MA, Helguera PR, Busciglio J. Rahman AS, et al. Among authors: busciglio j. J Vis Exp. 2010 Nov 11;(45):2384. doi: 10.3791/2384. J Vis Exp. 2010. PMID: 21113113 Free PMC article.

6

Nrf2 stabilization prevents critical oxidative damage in Down syndrome cells.

Zamponi E, Zamponi N, Coskun P, Quassollo G, Lorenzo A, Cannas SA, Pigino G, Chialvo DR, Gardiner K, Busciglio J, Helguera P. Zamponi E, et al. Among authors: busciglio j. Aging Cell. 2018 Oct;17(5):e12812. doi: 10.1111/acel.12812. Epub 2018 Jul 20. Aging Cell. 2018. PMID: 30028071 Free PMC article.

7

NAP and ADNF-9 protect normal and Down's syndrome cortical neurons from oxidative damage and apoptosis.

Busciglio J, Pelsman A, Helguera P, Ashur-Fabian O, Pinhasov A, Brenneman DE, Gozes I. Busciglio J, et al. Curr Pharm Des. 2007;13(11):1091-8. doi: 10.2174/138161207780618957. Curr Pharm Des. 2007. PMID: 17430172

8

Metabolic and Growth Rate Alterations in Lymphoblastic Cell Lines Discriminate Between Down Syndrome and Alzheimer's Disease.

Coskun P, Helguera P, Nemati Z, Bohannan RC, Thomas J, Samuel SE, Argueta J, Doran E, Wallace DC, Lott IT, Busciglio J. Coskun P, et al. Among authors: busciglio j. J Alzheimers Dis. 2017;55(2):737-748. doi: 10.3233/JAD-160278. J Alzheimers Dis. 2017. PMID: 27802222

9

Repurposing cancer drugs identifies kenpaullone which ameliorates pathologic pain in preclinical models via normalization of inhibitory neurotransmission.

Yeo M, Chen Y, Jiang C, Chen G, Wang K, Chandra S, Bortsov A, Lioudyno M, Zeng Q, Wang P, Wang Z, Busciglio J, Ji RR, Liedtke W. Yeo M, et al. Among authors: busciglio j. Nat Commun. 2021 Oct 27;12(1):6208. doi: 10.1038/s41467-021-26270-3. Nat Commun. 2021. PMID: 34707084 Free PMC article.

10

Phosphorylation of actin-depolymerizing factor/cofilin by LIM-kinase mediates amyloid beta-induced degeneration: a potential mechanism of neuronal dystrophy in Alzheimer's disease.

Heredia L, Helguera P, de Olmos S, Kedikian G, Solá Vigo F, LaFerla F, Staufenbiel M, de Olmos J, Busciglio J, Cáceres A, Lorenzo A. Heredia L, et al. Among authors: busciglio j. J Neurosci. 2006 Jun 14;26(24):6533-42. doi: 10.1523/JNEUROSCI.5567-05.2006. J Neurosci. 2006. PMID: 16775141 Free PMC article.

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