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The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells.
Wenzel J, Lampe J, Müller-Fielitz H, Schuster R, Zille M, Müller K, Krohn M, Körbelin J, Zhang L, Özorhan Ü, Neve V, Wagner JUG, Bojkova D, Shumliakivska M, Jiang Y, Fähnrich A, Ott F, Sencio V, Robil C, Pfefferle S, Sauve F, Coêlho CFF, Franz J, Spiecker F, Lembrich B, Binder S, Feller N, König P, Busch H, Collin L, Villaseñor R, Jöhren O, Altmeppen HC, Pasparakis M, Dimmeler S, Cinatl J, Püschel K, Zelic M, Ofengeim D, Stadelmann C, Trottein F, Nogueiras R, Hilgenfeld R, Glatzel M, Prevot V, Schwaninger M. Wenzel J, et al. Among authors: busch h. Nat Neurosci. 2021 Nov;24(11):1522-1533. doi: 10.1038/s41593-021-00926-1. Epub 2021 Oct 21. Nat Neurosci. 2021. PMID: 34675436 Free PMC article.
Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice.
Hirose M, Schilf P, Gupta Y, Zarse K, Künstner A, Fähnrich A, Busch H, Yin J, Wright MN, Ziegler A, Vallier M, Belheouane M, Baines JF, Tautz D, Johann K, Oelkrug R, Mittag J, Lehnert H, Othman A, Jöhren O, Schwaninger M, Prehn C, Adamski J, Shima K, Rupp J, Häsler R, Fuellen G, Köhling R, Ristow M, Ibrahim SM. Hirose M, et al. Among authors: busch h. Sci Rep. 2018 Apr 12;8(1):5872. doi: 10.1038/s41598-018-24290-6. Sci Rep. 2018. PMID: 29651131 Free PMC article.
Genetics and Omics Analysis of Autoimmune Skin Blistering Diseases.
Olbrich M, Künstner A, Witte M, Busch H, Fähnrich A. Olbrich M, et al. Among authors: busch h. Front Immunol. 2019 Oct 15;10:2327. doi: 10.3389/fimmu.2019.02327. eCollection 2019. Front Immunol. 2019. PMID: 31749790 Free PMC article. Review.
An integrated personal and population-based Egyptian genome reference.
Wohlers I, Künstner A, Munz M, Olbrich M, Fähnrich A, Calonga-Solís V, Ma C, Hirose M, El-Mosallamy S, Salama M, Busch H, Ibrahim S. Wohlers I, et al. Among authors: busch h. Nat Commun. 2020 Sep 18;11(1):4719. doi: 10.1038/s41467-020-17964-1. Nat Commun. 2020. PMID: 32948767 Free PMC article.
1,260 results