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HIV-1 Vpu restricts Fc-mediated effector functions in vivo.
Prévost J, Anand SP, Rajashekar JK, Zhu L, Richard J, Goyette G, Medjahed H, Gendron-Lepage G, Chen HC, Chen Y, Horwitz JA, Grunst MW, Zolla-Pazner S, Haynes BF, Burton DR, Flavell RA, Kirchhoff F, Hahn BH, Smith AB 3rd, Pazgier M, Nussenzweig MC, Kumar P, Finzi A. Prévost J, et al. Among authors: burton dr. Cell Rep. 2022 Nov 8;41(6):111624. doi: 10.1016/j.celrep.2022.111624. Cell Rep. 2022. PMID: 36351384 Free PMC article.
Complementary antibody lineages achieve neutralization breadth in an HIV-1 infected elite neutralizer.
van Schooten J, Schorcht A, Farokhi E, Umotoy JC, Gao H, van den Kerkhof TLGM, Dorning J, Rijkhold Meesters TG, van der Woude P, Burger JA, Bijl T, Ghalaiyini R, Torrents de la Peña A, Turner HL, Labranche CC, Stanfield RL, Sok D, Schuitemaker H, Montefiori DC, Burton DR, Ozorowski G, Seaman MS, Wilson IA, Sanders RW, Ward AB, van Gils MJ. van Schooten J, et al. Among authors: burton dr. PLoS Pathog. 2022 Nov 17;18(11):e1010945. doi: 10.1371/journal.ppat.1010945. eCollection 2022 Nov. PLoS Pathog. 2022. PMID: 36395347 Free PMC article.
Identification of an HIV-1 clade A envelope that exhibits broad antigenicity and neutralization sensitivity and elicits antibodies targeting three distinct epitopes.
Hoffenberg S, Powell R, Carpov A, Wagner D, Wilson A, Kosakovsky Pond S, Lindsay R, Arendt H, Destefano J, Phogat S, Poignard P, Fling SP, Simek M, Labranche C, Montefiori D, Wrin T, Phung P, Burton D, Koff W, King CR, Parks CL, Caulfield MJ. Hoffenberg S, et al. J Virol. 2013 May;87(10):5372-83. doi: 10.1128/JVI.02827-12. Epub 2013 Mar 6. J Virol. 2013. PMID: 23468492 Free PMC article.
Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire.
Altman PX, Ozorowski G, Stanfield RL, Haakenson J, Appel M, Parren M, Lee WH, Sang H, Woehl J, Saye-Francisco K, Joyce C, Song G, Porter K, Landais E, Andrabi R, Wilson IA, Ward AB, Mwangi W, Smider VV, Burton DR, Sok D. Altman PX, et al. Among authors: burton dr. bioRxiv [Preprint]. 2024 Feb 14:2024.02.13.580058. doi: 10.1101/2024.02.13.580058. bioRxiv. 2024. PMID: 38405899 Free PMC article. Preprint.
Synthetic development of a broadly neutralizing antibody against snake venom long-chain α-neurotoxins.
Khalek IS, Senji Laxme RR, Nguyen YTK, Khochare S, Patel RN, Woehl J, Smith JM, Saye-Francisco K, Kim Y, Misson Mindrebo L, Tran Q, Kędzior M, Boré E, Limbo O, Verma M, Stanfield RL, Menzies SK, Ainsworth S, Harrison RA, Burton DR, Sok D, Wilson IA, Casewell NR, Sunagar K, Jardine JG. Khalek IS, et al. Among authors: burton dr. Sci Transl Med. 2024 Feb 21;16(735):eadk1867. doi: 10.1126/scitranslmed.adk1867. Epub 2024 Feb 21. Sci Transl Med. 2024. PMID: 38381847
659 results