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Page 1
Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms.
Schugar RC, Gliniak CM, Osborn LJ, Massey W, Sangwan N, Horak A, Banerjee R, Orabi D, Helsley RN, Brown AL, Burrows A, Finney C, Fung KK, Allen FM, Ferguson D, Gromovsky AD, Neumann C, Cook K, McMillan A, Buffa JA, Anderson JT, Mehrabian M, Goudarzi M, Willard B, Mak TD, Armstrong AR, Swanson G, Keshavarzian A, Garcia-Garcia JC, Wang Z, Lusis AJ, Hazen SL, Brown JM. Schugar RC, et al. Among authors: burrows a. Elife. 2022 Jan 24;11:e63998. doi: 10.7554/eLife.63998. Elife. 2022. PMID: 35072627 Free PMC article.
The TMAO-Generating Enzyme Flavin Monooxygenase 3 Is a Central Regulator of Cholesterol Balance.
Warrier M, Shih DM, Burrows AC, Ferguson D, Gromovsky AD, Brown AL, Marshall S, McDaniel A, Schugar RC, Wang Z, Sacks J, Rong X, Vallim TA, Chou J, Ivanova PT, Myers DS, Brown HA, Lee RG, Crooke RM, Graham MJ, Liu X, Parini P, Tontonoz P, Lusis AJ, Hazen SL, Temel RE, Brown JM. Warrier M, et al. Among authors: burrows ac. Cell Rep. 2015 Jan 20;10(3):326-338. doi: 10.1016/j.celrep.2014.12.036. Epub 2015 Jan 15. Cell Rep. 2015. PMID: 25600868 Free PMC article.
Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation.
Lord CC, Ferguson D, Thomas G, Brown AL, Schugar RC, Burrows A, Gromovsky AD, Betters J, Neumann C, Sacks J, Marshall S, Watts R, Schweiger M, Lee RG, Crooke RM, Graham MJ, Lathia JD, Sakaguchi TF, Lehner R, Haemmerle G, Zechner R, Brown JM. Lord CC, et al. Among authors: burrows a. Cell Rep. 2016 Jul 26;16(4):939-949. doi: 10.1016/j.celrep.2016.06.049. Epub 2016 Jul 7. Cell Rep. 2016. PMID: 27396333 Free PMC article.
The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue.
Schugar RC, Shih DM, Warrier M, Helsley RN, Burrows A, Ferguson D, Brown AL, Gromovsky AD, Heine M, Chatterjee A, Li L, Li XS, Wang Z, Willard B, Meng Y, Kim H, Che N, Pan C, Lee RG, Crooke RM, Graham MJ, Morton RE, Langefeld CD, Das SK, Rudel LL, Zein N, McCullough AJ, Dasarathy S, Tang WHW, Erokwu BO, Flask CA, Laakso M, Civelek M, Naga Prasad SV, Heeren J, Lusis AJ, Hazen SL, Brown JM. Schugar RC, et al. Among authors: burrows a. Cell Rep. 2017 Jun 20;19(12):2451-2461. doi: 10.1016/j.celrep.2017.05.077. Cell Rep. 2017. PMID: 28636934 Free PMC article.
The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue.
Schugar RC, Shih DM, Warrier M, Helsley RN, Burrows A, Ferguson D, Brown AL, Gromovsky AD, Heine M, Chatterjee A, Li L, Li XS, Wang Z, Willard B, Meng Y, Kim H, Che N, Pan C, Lee RG, Crooke RM, Graham MJ, Morton RE, Langefeld CD, Das SK, Rudel LL, Zein N, McCullough AJ, Dasarathy S, Tang WHW, Erokwu BO, Flask CA, Laakso M, Civelek M, Naga Prasad SV, Heeren J, Lusis AJ, Hazen SL, Brown JM. Schugar RC, et al. Among authors: burrows a. Cell Rep. 2017 Jul 5;20(1):279. doi: 10.1016/j.celrep.2017.06.053. Cell Rep. 2017. PMID: 28683320 Free PMC article. No abstract available.
Δ-5 Fatty Acid Desaturase FADS1 Impacts Metabolic Disease by Balancing Proinflammatory and Proresolving Lipid Mediators.
Gromovsky AD, Schugar RC, Brown AL, Helsley RN, Burrows AC, Ferguson D, Zhang R, Sansbury BE, Lee RG, Morton RE, Allende DS, Parks JS, Spite M, Brown JM. Gromovsky AD, et al. Arterioscler Thromb Vasc Biol. 2018 Jan;38(1):218-231. doi: 10.1161/ATVBAHA.117.309660. Epub 2017 Oct 26. Arterioscler Thromb Vasc Biol. 2018. PMID: 29074585 Free PMC article.
Metaorganismal choline metabolism shapes olfactory perception.
Massey WJ, Kay KE, Jaramillo TC, Horak AJ 3rd, Cao S, Osborn LJ, Banerjee R, Mrdjen M, Hamoudi MK, Silver DJ, Burrows AC, Brown AL, Reizes O, Lathia JD, Wang Z, Hazen SL, Brown JM. Massey WJ, et al. J Biol Chem. 2023 Nov;299(11):105299. doi: 10.1016/j.jbc.2023.105299. Epub 2023 Sep 28. J Biol Chem. 2023. PMID: 37777156 Free PMC article.
The nonvesicular sterol transporter Aster-C plays a minor role in whole body cholesterol balance.
Banerjee R, Hohe RC, Cao S, Jung BM, Horak AJ, Ramachandiran I, Massey WJ, Varadharajan V, Zajczenko NI, Burrows AC, Dutta S, Goudarzi M, Mahen K, Carter A, Helsley RN, Gordon SM, Morton RE, Strauch C, Willard B, Gogonea CB, Gogonea V, Pedrelli M, Parini P, Brown JM. Banerjee R, et al. Among authors: burrows ac. Front Physiol. 2024 Apr 17;15:1371096. doi: 10.3389/fphys.2024.1371096. eCollection 2024. Front Physiol. 2024. PMID: 38694206 Free PMC article.
465 results