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Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition.
Rodriguez-Martin B, Alvarez EG, Baez-Ortega A, Zamora J, Supek F, Demeulemeester J, Santamarina M, Ju YS, Temes J, Garcia-Souto D, Detering H, Li Y, Rodriguez-Castro J, Dueso-Barroso A, Bruzos AL, Dentro SC, Blanco MG, Contino G, Ardeljan D, Tojo M, Roberts ND, Zumalave S, Edwards PA, Weischenfeldt J, Puiggròs M, Chong Z, Chen K, Lee EA, Wala JA, Raine KM, Butler A, Waszak SM, Navarro FCP, Schumacher SE, Monlong J, Maura F, Bolli N, Bourque G, Gerstein M, Park PJ, Wedge DC, Beroukhim R, Torrents D, Korbel JO, Martincorena I, Fitzgerald RC, Van Loo P, Kazazian HH, Burns KH; PCAWG Structural Variation Working Group; Campbell PJ, Tubio JMC; PCAWG Consortium. Rodriguez-Martin B, et al. Among authors: burns kh. Nat Genet. 2020 Mar;52(3):306-319. doi: 10.1038/s41588-019-0562-0. Epub 2020 Feb 5. Nat Genet. 2020. PMID: 32024998 Free PMC article.
Active transposition in genomes.
Huang CR, Burns KH, Boeke JD. Huang CR, et al. Among authors: burns kh. Annu Rev Genet. 2012;46:651-75. doi: 10.1146/annurev-genet-110711-155616. Annu Rev Genet. 2012. PMID: 23145912 Free PMC article. Review.
Functional impact of the human mobilome.
Babatz TD, Burns KH. Babatz TD, et al. Among authors: burns kh. Curr Opin Genet Dev. 2013 Jun;23(3):264-70. doi: 10.1016/j.gde.2013.02.007. Epub 2013 Mar 22. Curr Opin Genet Dev. 2013. PMID: 23523050 Free PMC article. Review.
Retrotransposon insertions in the clonal evolution of pancreatic ductal adenocarcinoma.
Rodić N, Steranka JP, Makohon-Moore A, Moyer A, Shen P, Sharma R, Kohutek ZA, Huang CR, Ahn D, Mita P, Taylor MS, Barker NJ, Hruban RH, Iacobuzio-Donahue CA, Boeke JD, Burns KH. Rodić N, et al. Among authors: burns kh. Nat Med. 2015 Sep;21(9):1060-4. doi: 10.1038/nm.3919. Epub 2015 Aug 10. Nat Med. 2015. PMID: 26259033 Free PMC article.
LINE-1 expression and retrotransposition in Barrett's esophagus and esophageal carcinoma.
Doucet-O'Hare TT, Rodić N, Sharma R, Darbari I, Abril G, Choi JA, Young Ahn J, Cheng Y, Anders RA, Burns KH, Meltzer SJ, Kazazian HH Jr. Doucet-O'Hare TT, et al. Among authors: burns kh. Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):E4894-900. doi: 10.1073/pnas.1502474112. Epub 2015 Aug 17. Proc Natl Acad Sci U S A. 2015. PMID: 26283398 Free PMC article.
Meeting Report: The Role of the Mobilome in Cancer.
Ardeljan D, Taylor MS, Burns KH, Boeke JD, Espey MG, Woodhouse EC, Howcroft TK. Ardeljan D, et al. Among authors: burns kh. Cancer Res. 2016 Aug 1;76(15):4316-9. doi: 10.1158/0008-5472.CAN-15-3421. Epub 2016 Jul 18. Cancer Res. 2016. PMID: 27527733 Free PMC article.
176 results