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Platelet Munc13-4 regulates hemostasis, thrombosis and airway inflammation.
Cardenas EI, Breaux K, Da Q, Flores JR, Ramos MA, Tuvim MJ, Burns AR, Rumbaut RE, Adachi R. Cardenas EI, et al. Among authors: burns ar. Haematologica. 2018 Jul;103(7):1235-1244. doi: 10.3324/haematol.2017.185637. Epub 2018 Apr 19. Haematologica. 2018. PMID: 29674495 Free PMC article.
Syntaxin 3, but not syntaxin 4, is required for mast cell-regulated exocytosis, where it plays a primary role mediating compound exocytosis.
Sanchez E, Gonzalez EA, Moreno DS, Cardenas RA, Ramos MA, Davalos AJ, Manllo J, Rodarte AI, Petrova Y, Moreira DC, Chavez MA, Tortoriello A, Lara A, Gutierrez BA, Burns AR, Heidelberger R, Adachi R. Sanchez E, et al. Among authors: burns ar. J Biol Chem. 2019 Mar 1;294(9):3012-3023. doi: 10.1074/jbc.RA118.005532. Epub 2018 Dec 18. J Biol Chem. 2019. PMID: 30563839 Free PMC article.
Munc13 proteins control regulated exocytosis in mast cells.
Rodarte EM, Ramos MA, Davalos AJ, Moreira DC, Moreno DS, Cardenas EI, Rodarte AI, Petrova Y, Molina S, Rendon LE, Sanchez E, Breaux K, Tortoriello A, Manllo J, Gonzalez EA, Tuvim MJ, Dickey BF, Burns AR, Heidelberger R, Adachi R. Rodarte EM, et al. Among authors: burns ar. J Biol Chem. 2018 Jan 5;293(1):345-358. doi: 10.1074/jbc.M117.816884. Epub 2017 Nov 15. J Biol Chem. 2018. PMID: 29141910 Free PMC article.
Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle-regulated exocytosis in mast cells.
Gutierrez BA, Chavez MA, Rodarte AI, Ramos MA, Dominguez A, Petrova Y, Davalos AJ, Costa RM, Elizondo R, Tuvim MJ, Dickey BF, Burns AR, Heidelberger R, Adachi R. Gutierrez BA, et al. Among authors: burns ar. J Biol Chem. 2018 May 11;293(19):7148-7159. doi: 10.1074/jbc.RA118.002455. Epub 2018 Mar 29. J Biol Chem. 2018. PMID: 29599294 Free PMC article.
Different Munc18 proteins mediate baseline and stimulated airway mucin secretion.
Jaramillo AM, Piccotti L, Velasco WV, Delgado ASH, Azzegagh Z, Chung F, Nazeer U, Farooq J, Brenner J, Parker-Thornburg J, Scott BL, Evans CM, Adachi R, Burns AR, Kreda SM, Tuvim MJ, Dickey BF. Jaramillo AM, et al. Among authors: burns ar. JCI Insight. 2019 Mar 21;4(6):e124815. doi: 10.1172/jci.insight.124815. eCollection 2019 Mar 21. JCI Insight. 2019. PMID: 30721150 Free PMC article.
Mucin is produced by clara cells in the proximal airways of antigen-challenged mice.
Evans CM, Williams OW, Tuvim MJ, Nigam R, Mixides GP, Blackburn MR, DeMayo FJ, Burns AR, Smith C, Reynolds SD, Stripp BR, Dickey BF. Evans CM, et al. Among authors: burns ar. Am J Respir Cell Mol Biol. 2004 Oct;31(4):382-94. doi: 10.1165/rcmb.2004-0060OC. Epub 2004 Jun 10. Am J Respir Cell Mol Biol. 2004. PMID: 15191915 Free PMC article.
187 results