Burkholder A - Search Results

1

Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice.

Aden K, Bartsch K, Dahl J, Reijns MAM, Esser D, Sheibani-Tezerji R, Sinha A, Wottawa F, Ito G, Mishra N, Knittler K, Burkholder A, Welz L, van Es J, Tran F, Lipinski S, Kakavand N, Boeger C, Lucius R, von Schoenfels W, Schafmayer C, Lenk L, Chalaris A, Clevers H, Röcken C, Kaleta C, Rose-John S, Schreiber S, Kunkel T, Rabe B, Rosenstiel P. Aden K, et al. Among authors: burkholder a. Gastroenterology. 2019 Jan;156(1):145-159.e19. doi: 10.1053/j.gastro.2018.09.047. Epub 2018 Sep 28. Gastroenterology. 2019. PMID: 30273559 Free PMC article.

2

Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition.

Lujan SA, Clausen AR, Clark AB, MacAlpine HK, MacAlpine DM, Malc EP, Mieczkowski PA, Burkholder AB, Fargo DC, Gordenin DA, Kunkel TA. Lujan SA, et al. Among authors: burkholder ab. Genome Res. 2014 Nov;24(11):1751-64. doi: 10.1101/gr.178335.114. Epub 2014 Sep 12. Genome Res. 2014. PMID: 25217194 Free PMC article.

3

Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation.

Clausen AR, Lujan SA, Burkholder AB, Orebaugh CD, Williams JS, Clausen MF, Malc EP, Mieczkowski PA, Fargo DC, Smith DJ, Kunkel TA. Clausen AR, et al. Among authors: burkholder ab. Nat Struct Mol Biol. 2015 Mar;22(3):185-91. doi: 10.1038/nsmb.2957. Epub 2015 Jan 26. Nat Struct Mol Biol. 2015. PMID: 25622295 Free PMC article.

4

Mapping Ribonucleotides Incorporated into DNA by Hydrolytic End-Sequencing.

Orebaugh CD, Lujan SA, Burkholder AB, Clausen AR, Kunkel TA. Orebaugh CD, et al. Among authors: burkholder ab. Methods Mol Biol. 2018;1672:329-345. doi: 10.1007/978-1-4939-7306-4_23. Methods Mol Biol. 2018. PMID: 29043634

5

Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae.

Garbacz MA, Lujan SA, Burkholder AB, Cox PB, Wu Q, Zhou ZX, Haber JE, Kunkel TA. Garbacz MA, et al. Among authors: burkholder ab. Nat Commun. 2018 Feb 27;9(1):858. doi: 10.1038/s41467-018-03270-4. Nat Commun. 2018. PMID: 29487291 Free PMC article.

6

Muver, a computational framework for accurately calling accumulated mutations.

Burkholder AB, Lujan SA, Lavender CA, Grimm SA, Kunkel TA, Fargo DC. Burkholder AB, et al. BMC Genomics. 2018 May 9;19(1):345. doi: 10.1186/s12864-018-4753-3. BMC Genomics. 2018. PMID: 29743009 Free PMC article.

7

Genome-wide mutagenesis resulting from topoisomerase 1-processing of unrepaired ribonucleotides in DNA.

Williams JS, Lujan SA, Zhou ZX, Burkholder AB, Clark AB, Fargo DC, Kunkel TA. Williams JS, et al. Among authors: burkholder ab. DNA Repair (Amst). 2019 Dec;84:102641. doi: 10.1016/j.dnarep.2019.102641. Epub 2019 Jul 3. DNA Repair (Amst). 2019. PMID: 31311768 Free PMC article.

8

Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication.

Zhou ZX, Lujan SA, Burkholder AB, Garbacz MA, Kunkel TA. Zhou ZX, et al. Among authors: burkholder ab. Nat Commun. 2019 Sep 5;10(1):3992. doi: 10.1038/s41467-019-11995-z. Nat Commun. 2019. PMID: 31488849 Free PMC article.

9

DNA Polymerase Delta Synthesizes Both Strands during Break-Induced Replication.

Donnianni RA, Zhou ZX, Lujan SA, Al-Zain A, Garcia V, Glancy E, Burkholder AB, Kunkel TA, Symington LS. Donnianni RA, et al. Among authors: burkholder ab. Mol Cell. 2019 Nov 7;76(3):371-381.e4. doi: 10.1016/j.molcel.2019.07.033. Epub 2019 Sep 5. Mol Cell. 2019. PMID: 31495565 Free PMC article.

10

The fidelity of DNA replication, particularly on GC-rich templates, is reduced by defects of the Fe-S cluster in DNA polymerase δ.

Kiktev DA, Dominska M, Zhang T, Dahl J, Stepchenkova EI, Mieczkowski P, Burgers PM, Lujan S, Burkholder A, Kunkel TA, Petes TD. Kiktev DA, et al. Among authors: burkholder a. Nucleic Acids Res. 2021 Jun 4;49(10):5623-5636. doi: 10.1093/nar/gkab371. Nucleic Acids Res. 2021. PMID: 34019669 Free PMC article.

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