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Simplified pretubulysin derivatives and their biological effects on cancer cells.
J Nat Prod. 2014 Mar 28;77(3):536-42. doi: 10.1021/np4008014. Epub 2014 Jan 17.
J Nat Prod. 2014.
PMID: 24437936
Anti-angiogenic effects of the tubulysin precursor pretubulysin and of simplified pretubulysin derivatives.
Rath S, Liebl J, Fürst R, Ullrich A, Burkhart JL, Kazmaier U, Herrmann J, Müller R, Günther M, Schreiner L, Wagner E, Vollmar AM, Zahler S.
Rath S, et al. Among authors: burkhart jl.
Br J Pharmacol. 2012 Nov;167(5):1048-61. doi: 10.1111/j.1476-5381.2012.02037.x.
Br J Pharmacol. 2012.
PMID: 22595030
Free PMC article.
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Pretubulysin derived probes as novel tools for monitoring the microtubule network via activity-based protein profiling and fluorescence microscopy.
Eirich J, Burkhart JL, Ullrich A, Rudolf GC, Vollmar A, Zahler S, Kazmaier U, Sieber SA.
Eirich J, et al. Among authors: burkhart jl.
Mol Biosyst. 2012 Aug;8(8):2067-75. doi: 10.1039/c2mb25144b. Epub 2012 Jun 21.
Mol Biosyst. 2012.
PMID: 22722320
Free article.
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Novel yeast bioassay for high-throughput screening of matrix metalloproteinase inhibitors.
Diehl B, Hoffmann TM, Mueller NC, Burkhart JL, Kazmaier U, Schmitt MJ.
Diehl B, et al. Among authors: burkhart jl.
Appl Environ Microbiol. 2011 Dec;77(24):8573-7. doi: 10.1128/AEM.06111-11. Epub 2011 Oct 14.
Appl Environ Microbiol. 2011.
PMID: 22003025
Free PMC article.
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Accelerated skin wound healing by selective 11β-Hydroxylase (CYP11B1) inhibitors.
Emmerich J, van Koppen CJ, Burkhart JL, Engeli RT, Hu Q, Odermatt A, Hartmann RW.
Emmerich J, et al. Among authors: burkhart jl.
Eur J Med Chem. 2018 Jan 1;143:591-597. doi: 10.1016/j.ejmech.2017.11.018. Epub 2017 Nov 21.
Eur J Med Chem. 2018.
PMID: 29207342
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Lead Optimization Generates CYP11B1 Inhibitors of Pyridylmethyl Isoxazole Type with Improved Pharmacological Profile for the Treatment of Cushing's Disease.
Emmerich J, van Koppen CJ, Burkhart JL, Hu Q, Siebenbürger L, Boerger C, Scheuer C, Laschke MW, Menger MD, Hartmann RW.
Emmerich J, et al. Among authors: burkhart jl.
J Med Chem. 2017 Jun 22;60(12):5086-5098. doi: 10.1021/acs.jmedchem.7b00437. Epub 2017 Jun 9.
J Med Chem. 2017.
PMID: 28570067
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