Burkard ME - Search Results

1

Plk1 protects kinetochore-centromere architecture against microtubule pulling forces.

Lera RF, Norman RX, Dumont M, Dennee A, Martin-Koob J, Fachinetti D, Burkard ME. Lera RF, et al. Among authors: burkard me. EMBO Rep. 2019 Oct 4;20(10):e48711. doi: 10.15252/embr.201948711. Epub 2019 Aug 30. EMBO Rep. 2019. PMID: 31468671 Free PMC article.

2

The final link: tapping the power of chemical genetics to connect the molecular and biologic functions of mitotic protein kinases.

Lera RF, Burkard ME. Lera RF, et al. Among authors: burkard me. Molecules. 2012 Oct 17;17(10):12172-86. doi: 10.3390/molecules171012172. Molecules. 2012. PMID: 23075814 Free PMC article. Review.

3

High mitotic activity of Polo-like kinase 1 is required for chromosome segregation and genomic integrity in human epithelial cells.

Lera RF, Burkard ME. Lera RF, et al. Among authors: burkard me. J Biol Chem. 2012 Dec 14;287(51):42812-25. doi: 10.1074/jbc.M112.412544. Epub 2012 Oct 27. J Biol Chem. 2012. PMID: 23105120 Free PMC article.

4

Interphase cytofission maintains genomic integrity of human cells after failed cytokinesis.

Choudhary A, Lera RF, Martowicz ML, Oxendine K, Laffin JJ, Weaver BA, Burkard ME. Choudhary A, et al. Among authors: burkard me. Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):13026-31. doi: 10.1073/pnas.1308203110. Epub 2013 Jul 22. Proc Natl Acad Sci U S A. 2013. PMID: 23878225 Free PMC article.

5

Centralspindlin assembly and 2 phosphorylations on MgcRacGAP by Polo-like kinase 1 initiate Ect2 binding in early cytokinesis.

Kim H, Guo F, Brahma S, Xing Y, Burkard ME. Kim H, et al. Among authors: burkard me. Cell Cycle. 2014;13(18):2952-61. doi: 10.4161/15384101.2014.947201. Cell Cycle. 2014. PMID: 25486482 Free PMC article.

6

Identification of Selective Lead Compounds for Treatment of High-Ploidy Breast Cancer.

Choudhary A, Zachek B, Lera RF, Zasadil LM, Lasek A, Denu RA, Kim H, Kanugh C, Laffin JJ, Harter JM, Wisinski KB, Saha S, Weaver BA, Burkard ME. Choudhary A, et al. Among authors: burkard me. Mol Cancer Ther. 2016 Jan;15(1):48-59. doi: 10.1158/1535-7163.MCT-15-0527. Epub 2015 Nov 19. Mol Cancer Ther. 2016. PMID: 26586723 Free PMC article.

7

Decoding Polo-like kinase 1 signaling along the kinetochore-centromere axis.

Lera RF, Potts GK, Suzuki A, Johnson JM, Salmon ED, Coon JJ, Burkard ME. Lera RF, et al. Among authors: burkard me. Nat Chem Biol. 2016 Jun;12(6):411-8. doi: 10.1038/nchembio.2060. Epub 2016 Apr 4. Nat Chem Biol. 2016. PMID: 27043190 Free PMC article.

8

Anillin Phosphorylation Controls Timely Membrane Association and Successful Cytokinesis.

Kim H, Johnson JM, Lera RF, Brahma S, Burkard ME. Kim H, et al. Among authors: burkard me. PLoS Genet. 2017 Jan 12;13(1):e1006511. doi: 10.1371/journal.pgen.1006511. eCollection 2017 Jan. PLoS Genet. 2017. PMID: 28081137 Free PMC article.

9

A Genetic Toggle for Chemical Control of Individual Plk1 Substrates.

Johnson JM, Hebert AS, Drane QH, Lera RF, Wan J, Weaver BA, Coon JJ, Burkard ME. Johnson JM, et al. Among authors: burkard me. Cell Chem Biol. 2020 Mar 19;27(3):350-362.e8. doi: 10.1016/j.chembiol.2020.01.007. Epub 2020 Feb 3. Cell Chem Biol. 2020. PMID: 32017920 Free PMC article.

10

Chromosomal instability upregulates interferon in acute myeloid leukemia.

Jin N, Lera RF, Yan RE, Guo F, Oxendine K, Horner VL, Hu Y, Wan J, Mattison RJ, Weaver BA, Burkard ME. Jin N, et al. Among authors: burkard me. Genes Chromosomes Cancer. 2020 Nov;59(11):627-638. doi: 10.1002/gcc.22880. Epub 2020 Jul 18. Genes Chromosomes Cancer. 2020. PMID: 32557940 Free PMC article.

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