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Tetherin antagonism by SARS-CoV-2 enhances virus release: multiple mechanisms including ORF3a-mediated defective retrograde traffic.
Stewart H, Palmulli R, Johansen KH, McGovern N, Shehata OM, Carnell GW, Jackson HK, Lee JS, Brown JC, Burgoyne T, Heeney JL, Okkenhaug K, Firth AE, Peden AA, Edgar JR. Stewart H, et al. Among authors: burgoyne t. bioRxiv [Preprint]. 2022 Dec 22:2021.01.06.425396. doi: 10.1101/2021.01.06.425396. bioRxiv. 2022. PMID: 33442692 Free PMC article. Updated. Preprint.
Combined approaches, including long-read sequencing, address the diagnostic challenge of HYDIN in primary ciliary dyskinesia.
Fleming A, Galey M, Briggs L, Edwards M, Hogg C, John S, Wilkinson S, Quinn E, Rai R, Burgoyne T, Rogers A, Patel MP, Griffin P, Muller S, Carr SB, Loebinger MR, Lucas JS, Shah A, Jose R, Mitchison HM, Shoemark A, Miller DE, Morris-Rosendahl DJ. Fleming A, et al. Among authors: burgoyne t. Eur J Hum Genet. 2024 Apr 11. doi: 10.1038/s41431-024-01599-7. Online ahead of print. Eur J Hum Genet. 2024. PMID: 38605126
Age-specific nasal epithelial responses to SARS-CoV-2 infection.
Woodall MNJ, Cujba AM, Worlock KB, Case KM, Masonou T, Yoshida M, Polanski K, Huang N, Lindeboom RGH, Mamanova L, Bolt L, Richardson L, Cakir B, Ellis S, Palor M, Burgoyne T, Pinto A, Moulding D, McHugh TD, Saleh A, Kilich E, Mehta P, O'Callaghan C, Zhou J, Barclay W, DeCoppi P, Butler CR, Cortina-Borja M, Vinette H, Roy S, Breuer J, Chambers RC, Heywood WE, Mills K, Hynds RE, Teichmann SA, Meyer KB, Nikolić MZ, Smith CM. Woodall MNJ, et al. Among authors: burgoyne t. Nat Microbiol. 2024 May;9(5):1293-1311. doi: 10.1038/s41564-024-01658-1. Epub 2024 Apr 15. Nat Microbiol. 2024. PMID: 38622380 Free PMC article.
Development and evaluation of a tool to optimise inhaler selection prior to hospital discharge following an exacerbation of COPD.
Price E, Ahmad S, Althobiani MA, Ayoob T, Burgoyne T, De Soyza A, Dobson M, Echevarria C, Martin G, Mendes RG, Preston AM, Rahman NM, Sapey E, Usmani OS, Hurst JR. Price E, et al. Among authors: burgoyne t. ERJ Open Res. 2024 Mar 4;10(2):00010-2024. doi: 10.1183/23120541.00010-2024. eCollection 2024 Mar. ERJ Open Res. 2024. PMID: 38444664 Free PMC article.
Loss of REP1 impacts choroidal melanogenesis and vasculogenesis in choroideremia.
Sarkar H, Tracey-White D, Hagag AM, Burgoyne T, Nair N, Jensen LD, Edwards MM, Moosajee M. Sarkar H, et al. Among authors: burgoyne t. Biochim Biophys Acta Mol Basis Dis. 2024 Feb;1870(2):166963. doi: 10.1016/j.bbadis.2023.166963. Epub 2023 Nov 20. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 37989423 Free article.
Tetherin antagonism by SARS-CoV-2 ORF3a and spike protein enhances virus release.
Stewart H, Palmulli R, Johansen KH, McGovern N, Shehata OM, Carnell GW, Jackson HK, Lee JS, Brown JC, Burgoyne T, Heeney JL, Okkenhaug K, Firth AE, Peden AA, Edgar JR. Stewart H, et al. Among authors: burgoyne t. EMBO Rep. 2023 Dec 6;24(12):e57224. doi: 10.15252/embr.202357224. Epub 2023 Oct 11. EMBO Rep. 2023. PMID: 37818801 Free PMC article.
81 results