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Intravenous injection of apolipoprotein A-V reconstituted high-density lipoprotein decreases hypertriglyceridemia in apoav-/- mice and requires glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1.
Shu X, Nelbach L, Weinstein MM, Burgess BL, Beckstead JA, Young SG, Ryan RO, Forte TM. Shu X, et al. Among authors: burgess bl. Arterioscler Thromb Vasc Biol. 2010 Dec;30(12):2504-9. doi: 10.1161/ATVBAHA.110.210815. Epub 2010 Oct 21. Arterioscler Thromb Vasc Biol. 2010. PMID: 20966404 Free PMC article.
Overexpression of human ABCG1 does not affect atherosclerosis in fat-fed ApoE-deficient mice.
Burgess B, Naus K, Chan J, Hirsch-Reinshagen V, Tansley G, Matzke L, Chan B, Wilkinson A, Fan J, Donkin J, Balik D, Tanaka T, Ou G, Dyer R, Innis S, McManus B, Lütjohann D, Wellington C. Burgess B, et al. Arterioscler Thromb Vasc Biol. 2008 Oct;28(10):1731-7. doi: 10.1161/ATVBAHA.108.168542. Epub 2008 Jul 3. Arterioscler Thromb Vasc Biol. 2008. PMID: 18599800
The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor protein.
Tansley GH, Burgess BL, Bryan MT, Su Y, Hirsch-Reinshagen V, Pearce J, Chan JY, Wilkinson A, Evans J, Naus KE, McIsaac S, Bromley K, Song W, Yang HC, Wang N, DeMattos RB, Wellington CL. Tansley GH, et al. Among authors: burgess bl. J Lipid Res. 2007 May;48(5):1022-34. doi: 10.1194/jlr.M600542-JLR200. Epub 2007 Feb 10. J Lipid Res. 2007. PMID: 17293612 Free article.
ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo.
Burgess BL, Parkinson PF, Racke MM, Hirsch-Reinshagen V, Fan J, Wong C, Stukas S, Theroux L, Chan JY, Donkin J, Wilkinson A, Balik D, Christie B, Poirier J, Lütjohann D, Demattos RB, Wellington CL. Burgess BL, et al. J Lipid Res. 2008 Jun;49(6):1254-67. doi: 10.1194/jlr.M700481-JLR200. Epub 2008 Feb 26. J Lipid Res. 2008. PMID: 18314463 Free article.
Why lipids are important for Alzheimer disease?
Hirsch-Reinshagen V, Burgess BL, Wellington CL. Hirsch-Reinshagen V, et al. Among authors: burgess bl. Mol Cell Biochem. 2009 Jun;326(1-2):121-9. doi: 10.1007/s11010-008-0012-2. Epub 2008 Dec 31. Mol Cell Biochem. 2009. PMID: 19116777
Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain.
Hirsch-Reinshagen V, Zhou S, Burgess BL, Bernier L, McIsaac SA, Chan JY, Tansley GH, Cohn JS, Hayden MR, Wellington CL. Hirsch-Reinshagen V, et al. Among authors: burgess bl. J Biol Chem. 2004 Sep 24;279(39):41197-207. doi: 10.1074/jbc.M407962200. Epub 2004 Jul 21. J Biol Chem. 2004. PMID: 15269218 Free article.
The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease.
Hirsch-Reinshagen V, Maia LF, Burgess BL, Blain JF, Naus KE, McIsaac SA, Parkinson PF, Chan JY, Tansley GH, Hayden MR, Poirier J, Van Nostrand W, Wellington CL. Hirsch-Reinshagen V, et al. Among authors: burgess bl. J Biol Chem. 2005 Dec 30;280(52):43243-56. doi: 10.1074/jbc.M508781200. Epub 2005 Oct 5. J Biol Chem. 2005. PMID: 16207707 Free article.
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