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A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monkeys.
St Andre M, Johnson M, Bansal PN, Wellen J, Robertson A, Opsahl A, Burch PM, Bialek P, Morris C, Owens J. St Andre M, et al. Among authors: burch pm. Skelet Muscle. 2017 Nov 9;7(1):25. doi: 10.1186/s13395-017-0141-y. Skelet Muscle. 2017. PMID: 29121992 Free PMC article.
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