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Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation.
Friedbichler K, Kerenyi MA, Kovacic B, Li G, Hoelbl A, Yahiaoui S, Sexl V, Müllner EW, Fajmann S, Cerny-Reiterer S, Valent P, Beug H, Gouilleux F, Bunting KD, Moriggl R. Friedbichler K, et al. Among authors: bunting kd. Blood. 2010 Sep 2;116(9):1548-58. doi: 10.1182/blood-2009-12-258913. Epub 2010 May 27. Blood. 2010. PMID: 20508164 Free PMC article.
Oncogenic STAT5 signaling promotes oxidative stress in chronic myeloid leukemia cells by repressing antioxidant defenses.
Bourgeais J, Ishac N, Medrzycki M, Brachet-Botineau M, Desbourdes L, Gouilleux-Gruart V, Pecnard E, Rouleux-Bonnin F, Gyan E, Domenech J, Mazurier F, Moriggl R, Bunting KD, Herault O, Gouilleux F. Bourgeais J, et al. Among authors: bunting kd. Oncotarget. 2017 Jun 27;8(26):41876-41889. doi: 10.18632/oncotarget.11480. Oncotarget. 2017. PMID: 27566554 Free PMC article.
Stat5 tetramer formation is associated with leukemogenesis.
Moriggl R, Sexl V, Kenner L, Duntsch C, Stangl K, Gingras S, Hoffmeyer A, Bauer A, Piekorz R, Wang D, Bunting KD, Wagner EF, Sonneck K, Valent P, Ihle JN, Beug H. Moriggl R, et al. Among authors: bunting kd. Cancer Cell. 2005 Jan;7(1):87-99. doi: 10.1016/j.ccr.2004.12.010. Cancer Cell. 2005. PMID: 15652752 Free article.
AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis.
Park J, Schlederer M, Schreiber M, Ice R, Merkel O, Bilban M, Hofbauer S, Kim S, Addison J, Zou J, Ji C, Bunting ST, Wang Z, Shoham M, Huang G, Bago-Horvath Z, Gibson LF, Rojanasakul Y, Remick S, Ivanov A, Pugacheva E, Bunting KD, Moriggl R, Kenner L, Tse W. Park J, et al. Among authors: bunting kd, bunting st. Oncotarget. 2015 Aug 21;6(24):20697-710. doi: 10.18632/oncotarget.4136. Oncotarget. 2015. PMID: 26079538 Free PMC article.
102 results