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An investigation of p53 in skeletal muscle aging.
Ebert SM, Dierdorff JM, Meyerholz DK, Bullard SA, Al-Zougbi A, DeLau AD, Tomcheck KC, Skopec ZP, Marcotte GR, Bodine SC, Adams CM. Ebert SM, et al. Among authors: bullard sa. J Appl Physiol (1985). 2019 Oct 1;127(4):1075-1084. doi: 10.1152/japplphysiol.00363.2019. Epub 2019 Aug 29. J Appl Physiol (1985). 2019. PMID: 31465716 Free PMC article.
Spermine oxidase maintains basal skeletal muscle gene expression and fiber size and is strongly repressed by conditions that cause skeletal muscle atrophy.
Bongers KS, Fox DK, Kunkel SD, Stebounova LV, Murry DJ, Pufall MA, Ebert SM, Dyle MC, Bullard SA, Dierdorff JM, Adams CM. Bongers KS, et al. Among authors: bullard sa. Am J Physiol Endocrinol Metab. 2015 Jan 15;308(2):E144-58. doi: 10.1152/ajpendo.00472.2014. Epub 2014 Nov 18. Am J Physiol Endocrinol Metab. 2015. PMID: 25406264 Free PMC article.
Identification and Small Molecule Inhibition of an Activating Transcription Factor 4 (ATF4)-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy.
Ebert SM, Dyle MC, Bullard SA, Dierdorff JM, Murry DJ, Fox DK, Bongers KS, Lira VA, Meyerholz DK, Talley JJ, Adams CM. Ebert SM, et al. Among authors: bullard sa. J Biol Chem. 2015 Oct 16;290(42):25497-511. doi: 10.1074/jbc.M115.681445. Epub 2015 Sep 3. J Biol Chem. 2015. PMID: 26338703 Free PMC article.
Activating transcription factor 4 (ATF4) promotes skeletal muscle atrophy by forming a heterodimer with the transcriptional regulator C/EBPβ.
Ebert SM, Bullard SA, Basisty N, Marcotte GR, Skopec ZP, Dierdorff JM, Al-Zougbi A, Tomcheck KC, DeLau AD, Rathmacher JA, Bodine SC, Schilling B, Adams CM. Ebert SM, et al. Among authors: bullard sa. J Biol Chem. 2020 Feb 28;295(9):2787-2803. doi: 10.1074/jbc.RA119.012095. Epub 2020 Jan 17. J Biol Chem. 2020. PMID: 31953319 Free PMC article.
143 results