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The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity.
Baumgartner CK, Ebrahimi-Nik H, Iracheta-Vellve A, Hamel KM, Olander KE, Davis TGR, McGuire KA, Halvorsen GT, Avila OI, Patel CH, Kim SY, Kammula AV, Muscato AJ, Halliwill K, Geda P, Klinge KL, Xiong Z, Duggan R, Mu L, Yeary MD, Patti JC, Balon TM, Mathew R, Backus C, Kennedy DE, Chen A, Longenecker K, Klahn JT, Hrusch CL, Krishnan N, Hutchins CW, Dunning JP, Bulic M, Tiwari P, Colvin KJ, Chuong CL, Kohnle IC, Rees MG, Boghossian A, Ronan M, Roth JA, Wu MJ, Suermondt JSMT, Knudsen NH, Cheruiyot CK, Sen DR, Griffin GK, Golub TR, El-Bardeesy N, Decker JH, Yang Y, Guffroy M, Fossey S, Trusk P, Sun IM, Liu Y, Qiu W, Sun Q, Paddock MN, Farney EP, Matulenko MA, Beauregard C, Frost JM, Yates KB, Kym PR, Manguso RT. Baumgartner CK, et al. Among authors: bulic m. Nature. 2023 Oct;622(7984):850-862. doi: 10.1038/s41586-023-06575-7. Epub 2023 Oct 4. Nature. 2023. PMID: 37794185 Free PMC article.
Toll-like receptor-3 contributes to the development of aortic valve stenosis.
Niepmann ST, Willemsen N, Boucher AS, Stei M, Goody P, Zietzer A, Bulic M, Billig H, Odainic A, Weisheit CK, Quast C, Adam M, Schmidt SV, Bakhtiary F, Jansen F, Nickenig G, Latz E, Zimmer S. Niepmann ST, et al. Among authors: bulic m. Basic Res Cardiol. 2023 Feb 1;118(1):6. doi: 10.1007/s00395-023-00980-9. Basic Res Cardiol. 2023. PMID: 36723728 Free PMC article.
Large extracellular vesicles in the left atrial appendage in patients with atrial fibrillation-the missing link?
Zietzer A, Al-Kassou B, Jamme P, Rolfes V, Steffen E, Bulic M, Hosen MR, Goody PR, Tiyerili V, Zimmer S, Schrickel JW, Sedaghat A, Franklin BS, Werner N, Nickenig G, Jansen F. Zietzer A, et al. Among authors: bulic m. Clin Res Cardiol. 2022 Jan;111(1):34-49. doi: 10.1007/s00392-021-01873-4. Epub 2021 Jun 1. Clin Res Cardiol. 2022. PMID: 34061226 Free PMC article.
LKB1/STK11 Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms.
Marinaccio C, Suraneni P, Celik H, Volk A, Wen QJ, Ling T, Bulic M, Lasho T, Koche RP, Famulare CA, Farnoud N, Stein B, Schieber M, Gurbuxani S, Root DE, Younger ST, Hoffman R, Gangat N, Ntziachristos P, Chandel NS, Levine RL, Rampal RK, Challen GA, Tefferi A, Crispino JD. Marinaccio C, et al. Among authors: bulic m. Cancer Discov. 2021 Jun;11(6):1398-1410. doi: 10.1158/2159-8290.CD-20-1353. Epub 2021 Feb 12. Cancer Discov. 2021. PMID: 33579786 Free PMC article.
Activation of JAK/STAT Signaling in Megakaryocytes Sustains Myeloproliferation In Vivo.
Woods B, Chen W, Chiu S, Marinaccio C, Fu C, Gu L, Bulic M, Yang Q, Zouak A, Jia S, Suraneni PK, Xu K, Levine RL, Crispino JD, Wen QJ. Woods B, et al. Among authors: bulic m. Clin Cancer Res. 2019 Oct 1;25(19):5901-5912. doi: 10.1158/1078-0432.CCR-18-4089. Epub 2019 Jun 19. Clin Cancer Res. 2019. PMID: 31217200 Free PMC article.
A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis.
Volk A, Liang K, Suraneni P, Li X, Zhao J, Bulic M, Marshall S, Pulakanti K, Malinge S, Taub J, Ge Y, Rao S, Bartom E, Shilatifard A, Crispino JD. Volk A, et al. Among authors: bulic m. Cancer Cell. 2018 Nov 12;34(5):707-723.e7. doi: 10.1016/j.ccell.2018.10.004. Cancer Cell. 2018. PMID: 30423293 Free PMC article.
AKT activation is a feature of CALR mutant myeloproliferative neoplasms.
Fu C, Wen QJ, Marinaccio C, Ling T, Chen W, Bulic M, Lasho T, Tefferi A, Crispino JD, Xu K. Fu C, et al. Among authors: bulic m. Leukemia. 2019 Jan;33(1):271-274. doi: 10.1038/s41375-018-0224-8. Epub 2018 Aug 6. Leukemia. 2019. PMID: 30082822 Free PMC article. No abstract available.
40 results