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Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice.
Stancu IC, Vasconcelos B, Ris L, Wang P, Villers A, Peeraer E, Buist A, Terwel D, Baatsen P, Oyelami T, Pierrot N, Casteels C, Bormans G, Kienlen-Campard P, Octave JN, Moechars D, Dewachter I. Stancu IC, et al. Among authors: buist a. Acta Neuropathol. 2015 Jun;129(6):875-94. doi: 10.1007/s00401-015-1413-4. Epub 2015 Apr 11. Acta Neuropathol. 2015. PMID: 25862635 Free PMC article.
Synaptic Contacts Enhance Cell-to-Cell Tau Pathology Propagation.
Calafate S, Buist A, Miskiewicz K, Vijayan V, Daneels G, de Strooper B, de Wit J, Verstreken P, Moechars D. Calafate S, et al. Among authors: buist a. Cell Rep. 2015 May 26;11(8):1176-83. doi: 10.1016/j.celrep.2015.04.043. Epub 2015 May 14. Cell Rep. 2015. PMID: 25981034 Free article.
Using Human iPSC-Derived Neurons to Model TAU Aggregation.
Verheyen A, Diels A, Dijkmans J, Oyelami T, Meneghello G, Mertens L, Versweyveld S, Borgers M, Buist A, Peeters P, Cik M. Verheyen A, et al. Among authors: buist a. PLoS One. 2015 Dec 31;10(12):e0146127. doi: 10.1371/journal.pone.0146127. eCollection 2015. PLoS One. 2015. PMID: 26720731 Free PMC article.
Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo.
Vasconcelos B, Stancu IC, Buist A, Bird M, Wang P, Vanoosthuyse A, Van Kolen K, Verheyen A, Kienlen-Campard P, Octave JN, Baatsen P, Moechars D, Dewachter I. Vasconcelos B, et al. Among authors: buist a. Acta Neuropathol. 2016 Apr;131(4):549-69. doi: 10.1007/s00401-015-1525-x. Epub 2016 Jan 6. Acta Neuropathol. 2016. PMID: 26739002 Free PMC article.
Development of a Scalable, High-Throughput-Compatible Assay to Detect Tau Aggregates Using iPSC-Derived Cortical Neurons Maintained in a Three-Dimensional Culture Format.
Medda X, Mertens L, Versweyveld S, Diels A, Barnham L, Bretteville A, Buist A, Verheyen A, Royaux I, Ebneth A, Cabrera-Socorro A. Medda X, et al. Among authors: buist a. J Biomol Screen. 2016 Sep;21(8):804-15. doi: 10.1177/1087057116638029. Epub 2016 Mar 16. J Biomol Screen. 2016. PMID: 26984927
Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.
Wang P, Joberty G, Buist A, Vanoosthuyse A, Stancu IC, Vasconcelos B, Pierrot N, Faelth-Savitski M, Kienlen-Campard P, Octave JN, Bantscheff M, Drewes G, Moechars D, Dewachter I. Wang P, et al. Among authors: buist a. Acta Neuropathol. 2017 May;133(5):731-749. doi: 10.1007/s00401-016-1663-9. Epub 2017 Jan 12. Acta Neuropathol. 2017. PMID: 28083634 Free PMC article.
Mutated Toll-like receptor 9 increases Alzheimer's disease risk by compromising innate immunity protection.
Cacace R, Zhou L, Hendrickx Van de Craen E, Buist A, Hoogmartens J, Sieben A, Cras P, Vandenberghe R, De Deyn PP, Oehlrich D, De Bondt A, Engelborghs S, Moechars D, Van Broeckhoven C. Cacace R, et al. Among authors: buist a. Mol Psychiatry. 2023 Dec;28(12):5380-5389. doi: 10.1038/s41380-023-02166-0. Epub 2023 Jul 11. Mol Psychiatry. 2023. PMID: 37433968 Free PMC article.
341 results