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Targeting DDX3X Helicase Activity with BA103 Shows Promising Therapeutic Effects in Preclinical Glioblastoma Models.
Brai A, Riva V, Clementi L, Falsitta L, Zamperini C, Sinigiani V, Festuccia C, Sabetta S, Aiello D, Roselli C, Garbelli A, Trivisani CI, Maccari L, Bugli F, Sanguinetti M, Calandro P, Chiariello M, Quaranta P, Botta L, Angelucci A, Maga G, Botta M. Brai A, et al. Among authors: bugli f. Cancers (Basel). 2021 Nov 7;13(21):5569. doi: 10.3390/cancers13215569. Cancers (Basel). 2021. PMID: 34771731 Free PMC article.
Biological Characterization and in Vivo Assessment of the Activity of a New Synthetic Macrocyclic Antifungal Compound.
Deodato D, Maccari G, De Luca F, Sanfilippo S, Casian A, Martini R, D'Arezzo S, Bonchi C, Bugli F, Posteraro B, Vandeputte P, Sanglard D, Docquier JD, Sanguinetti M, Visca P, Botta M. Deodato D, et al. Among authors: bugli f. J Med Chem. 2016 Apr 28;59(8):3854-66. doi: 10.1021/acs.jmedchem.6b00018. Epub 2016 Apr 19. J Med Chem. 2016. PMID: 27045868
Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents.
Brai A, Fazi R, Tintori C, Zamperini C, Bugli F, Sanguinetti M, Stigliano E, Esté J, Badia R, Franco S, Martinez MA, Martinez JP, Meyerhans A, Saladini F, Zazzi M, Garbelli A, Maga G, Botta M. Brai A, et al. Among authors: bugli f. Proc Natl Acad Sci U S A. 2016 May 10;113(19):5388-93. doi: 10.1073/pnas.1522987113. Epub 2016 Apr 26. Proc Natl Acad Sci U S A. 2016. PMID: 27118832 Free PMC article.
A protein chimera self-assembling unit for drug delivery.
Amalfitano A, Martini C, Nocca G, Papi M, De Spirito M, Sanguinetti M, Vitali A, Bugli F, Arcovito A. Amalfitano A, et al. Among authors: bugli f. Biotechnol Prog. 2019 Mar;35(2):e2769. doi: 10.1002/btpr.2769. Epub 2018 Dec 27. Biotechnol Prog. 2019. PMID: 30575331
Fish-derived antimicrobial peptides: Activity of a chionodracine mutant against bacterial models and human bacterial pathogens.
Buonocore F, Picchietti S, Porcelli F, Della Pelle G, Olivieri C, Poerio E, Bugli F, Menchinelli G, Sanguinetti M, Bresciani A, Gennari N, Taddei AR, Fausto AM, Scapigliati G. Buonocore F, et al. Among authors: bugli f. Dev Comp Immunol. 2019 Jul;96:9-17. doi: 10.1016/j.dci.2019.02.012. Epub 2019 Feb 18. Dev Comp Immunol. 2019. PMID: 30790604
A New Strategy for Glioblastoma Treatment: In Vitro and In Vivo Preclinical Characterization of Si306, a Pyrazolo[3,4-d]Pyrimidine Dual Src/P-Glycoprotein Inhibitor.
Fallacara AL, Zamperini C, Podolski-Renić A, Dinić J, Stanković T, Stepanović M, Mancini A, Rango E, Iovenitti G, Molinari A, Bugli F, Sanguinetti M, Torelli R, Martini M, Maccari L, Valoti M, Dreassi E, Botta M, Pešić M, Schenone S. Fallacara AL, et al. Among authors: bugli f. Cancers (Basel). 2019 Jun 19;11(6):848. doi: 10.3390/cancers11060848. Cancers (Basel). 2019. PMID: 31248184 Free PMC article.
88 results