Bugge TH - Search Results

1

Membrane-anchored Serine Protease Matriptase Is a Trigger of Pulmonary Fibrogenesis.

Bardou O, Menou A, François C, Duitman JW, von der Thüsen JH, Borie R, Sales KU, Mutze K, Castier Y, Sage E, Liu L, Bugge TH, Fairlie DP, Königshoff M, Crestani B, Borensztajn KS. Bardou O, et al. Among authors: bugge th. Am J Respir Crit Care Med. 2016 Apr 15;193(8):847-60. doi: 10.1164/rccm.201502-0299OC. Am J Respir Crit Care Med. 2016. PMID: 26599507 Free PMC article.

2

Type II transmembrane serine proteases.

Szabo R, Wu Q, Dickson RB, Netzel-Arnett S, Antalis TM, Bugge TH. Szabo R, et al. Among authors: bugge th. Thromb Haemost. 2003 Aug;90(2):185-93. doi: 10.1160/TH03-02-0071. Thromb Haemost. 2003. PMID: 12888865 Review.

3

Matriptase-3 is a novel phylogenetically preserved membrane-anchored serine protease with broad serpin reactivity.

Szabo R, Netzel-Arnett S, Hobson JP, Antalis TM, Bugge TH. Szabo R, et al. Among authors: bugge th. Biochem J. 2005 Aug 15;390(Pt 1):231-42. doi: 10.1042/BJ20050299. Biochem J. 2005. PMID: 15853774 Free PMC article.

4

Matriptase: potent proteolysis on the cell surface.

List K, Bugge TH, Szabo R. List K, et al. Among authors: bugge th. Mol Med. 2006 Jan-Mar;12(1-3):1-7. doi: 10.2119/2006-00022.List. Mol Med. 2006. PMID: 16838070 Free PMC article. Review.

5

Co-localization of the channel activating protease prostasin/(CAP1/PRSS8) with its candidate activator, matriptase.

List K, Hobson JP, Molinolo A, Bugge TH. List K, et al. Among authors: bugge th. J Cell Physiol. 2007 Oct;213(1):237-45. doi: 10.1002/jcp.21115. J Cell Physiol. 2007. PMID: 17471493

6

Potent inhibition and global co-localization implicate the transmembrane Kunitz-type serine protease inhibitor hepatocyte growth factor activator inhibitor-2 in the regulation of epithelial matriptase activity.

Szabo R, Hobson JP, List K, Molinolo A, Lin CY, Bugge TH. Szabo R, et al. Among authors: bugge th. J Biol Chem. 2008 Oct 24;283(43):29495-504. doi: 10.1074/jbc.M801970200. Epub 2008 Aug 19. J Biol Chem. 2008. PMID: 18713750 Free PMC article.

7

Epithelial integrity is maintained by a matriptase-dependent proteolytic pathway.

List K, Kosa P, Szabo R, Bey AL, Wang CB, Molinolo A, Bugge TH. List K, et al. Among authors: bugge th. Am J Pathol. 2009 Oct;175(4):1453-63. doi: 10.2353/ajpath.2009.090240. Epub 2009 Aug 28. Am J Pathol. 2009. PMID: 19717635 Free PMC article.

8

Membrane-anchored serine protease matriptase regulates epithelial barrier formation and permeability in the intestine.

Buzza MS, Netzel-Arnett S, Shea-Donohue T, Zhao A, Lin CY, List K, Szabo R, Fasano A, Bugge TH, Antalis TM. Buzza MS, et al. Among authors: bugge th. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4200-5. doi: 10.1073/pnas.0903923107. Epub 2010 Feb 8. Proc Natl Acad Sci U S A. 2010. PMID: 20142489 Free PMC article.

9

Matriptase initiates activation of epidermal pro-kallikrein and disease onset in a mouse model of Netherton syndrome.

Sales KU, Masedunskas A, Bey AL, Rasmussen AL, Weigert R, List K, Szabo R, Overbeek PA, Bugge TH. Sales KU, et al. Among authors: bugge th. Nat Genet. 2010 Aug;42(8):676-83. doi: 10.1038/ng.629. Epub 2010 Jul 25. Nat Genet. 2010. PMID: 20657595 Free PMC article.

10

c-Met-induced epithelial carcinogenesis is initiated by the serine protease matriptase.

Szabo R, Rasmussen AL, Moyer AB, Kosa P, Schafer JM, Molinolo AA, Gutkind JS, Bugge TH. Szabo R, et al. Among authors: bugge th. Oncogene. 2011 Apr 28;30(17):2003-16. doi: 10.1038/onc.2010.586. Epub 2011 Jan 10. Oncogene. 2011. PMID: 21217780 Free PMC article.

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