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Degradation of 5hmC-marked stalled replication forks by APE1 causes genomic instability.
Kharat SS, Ding X, Swaminathan D, Suresh A, Singh M, Sengodan SK, Burkett S, Marks H, Pamala C, He Y, Fox SD, Buehler EC, Muegge K, Martin SE, Sharan SK. Kharat SS, et al. Among authors: buehler ec. Sci Signal. 2020 Aug 18;13(645):eaba8091. doi: 10.1126/scisignal.aba8091. Sci Signal. 2020. PMID: 32817374 Free PMC article.
Synthetic viability by BRCA2 and PARP1/ARTD1 deficiencies.
Ding X, Ray Chaudhuri A, Callen E, Pang Y, Biswas K, Klarmann KD, Martin BK, Burkett S, Cleveland L, Stauffer S, Sullivan T, Dewan A, Marks H, Tubbs AT, Wong N, Buehler E, Akagi K, Martin SE, Keller JR, Nussenzweig A, Sharan SK. Ding X, et al. Nat Commun. 2016 Aug 8;7:12425. doi: 10.1038/ncomms12425. Nat Commun. 2016. PMID: 27498558 Free PMC article.
A genome-wide screen uncovers multiple roles for mitochondrial nucleoside diphosphate kinase D in inflammasome activation.
Ernst O, Sun J, Lin B, Banoth B, Dorrington MG, Liang J, Schwarz B, Stromberg KA, Katz S, Vayttaden SJ, Bradfield CJ, Slepushkina N, Rice CM, Buehler E, Khillan JS, McVicar DW, Bosio CM, Bryant CE, Sutterwala FS, Martin SE, Lal-Nag M, Fraser IDC. Ernst O, et al. Sci Signal. 2021 Aug 3;14(694):eabe0387. doi: 10.1126/scisignal.abe0387. Sci Signal. 2021. PMID: 34344832 Free PMC article.
Erratum for Sivan et al., "Identification of Restriction Factors by Human Genome-Wide RNA Interference Screening of Viral Host Range Mutants Exemplified by Discovery of SAMD9 and WDR6 as Inhibitors of the Vaccinia Virus K1L-C7L- Mutant".
Sivan G, Ormanoglu P, Buehler EC, Martin SE, Moss B. Sivan G, et al. Among authors: buehler ec. mBio. 2017 Oct 31;8(5):e01735-17. doi: 10.1128/mBio.01735-17. mBio. 2017. PMID: 29089434 Free PMC article. No abstract available.
29 results