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Effects of gel volume on pharmacokinetics for vaginal and rectal applications of combination DuoGel-IQB4012, a dual chamber-dual drug HIV microbicide gel, in pigtailed macaques.
Pereira LE, Singletary T, Martin A, Dinh CT, Deyounks F, Holder A, McNicholl J, Buckheit KW, Buckheit RW Jr, Ham A, Katz DF, Smith JM. Pereira LE, et al. Among authors: buckheit kw. Drug Deliv Transl Res. 2018 Oct;8(5):1180-1190. doi: 10.1007/s13346-018-0538-0. Drug Deliv Transl Res. 2018. PMID: 29761350 Free PMC article.
Pharmacokinetic and Pharmacodynamic Evaluation following Vaginal Application of IQB3002, a Dual-Chamber Microbicide Gel Containing the Nonnucleoside Reverse Transcriptase Inhibitor IQP-0528 in Rhesus Macaques.
Pereira LE, Mesquita PM, Ham A, Singletary T, Deyounks F, Martin A, McNicholl J, Buckheit KW, Buckheit RW Jr, Smith JM. Pereira LE, et al. Among authors: buckheit kw. Antimicrob Agents Chemother. 2015 Dec 14;60(3):1393-400. doi: 10.1128/AAC.02201-15. Antimicrob Agents Chemother. 2015. PMID: 26666935 Free PMC article.
The Role of Volume in the Perceptibility of Topical Vaginal Formulations: User Sensory Perceptions and Experiences of Heterosexual Couples During Vaginal Sex.
Guthrie KM, Fava JL, Vargas SE, Rosen RK, Shaw JG, Kojic EM, Ham AS, Rohan LC, Katz D, Panameño A, Colleran C, Friend DF, Buckheit KW, Buckheit RW Jr. Guthrie KM, et al. Among authors: buckheit kw. AIDS Res Hum Retroviruses. 2020 Dec;36(12):1059-1070. doi: 10.1089/AID.2020.0138. Epub 2020 Nov 3. AIDS Res Hum Retroviruses. 2020. PMID: 32988214 Free PMC article.
Examining the Safety, Pharmacokinetics, and Pharmacodynamics of a Rectally Administered IQP-0528 Gel for HIV Pre-Exposure Prophylaxis: A First-In-Human Study.
Al-Khouja A, Shieh E, Fuchs EJ, Marzinke MA, Bakshi RP, Hummert P, Ham AS, Buckheit KW, Breakey J, Weld ED, Chen H, Caffo BS, Buckheit RW, Hendrix CW. Al-Khouja A, et al. Among authors: buckheit kw. AIDS Res Hum Retroviruses. 2021 Jun;37(6):444-452. doi: 10.1089/AID.2020.0188. Epub 2021 Jan 25. AIDS Res Hum Retroviruses. 2021. PMID: 33371779 Free PMC article. Clinical Trial.
Designing Dual Compartment HIV Prevention Products: Women's Sensory Perceptions and Experiences of Suppositories for Rectal and Vaginal Use.
Guthrie KM, Rosen RK, Guillen M, Ramirez JJ, Vargas SE, Fava JL, Ham AS, Katz DF, Cu-Uvin S, Tumilty S, Smith KA, Buckheit KW, Buckheit RW , Jr. Guthrie KM, et al. Among authors: buckheit kw. AIDS Res Hum Retroviruses. 2022 Jul;38(7):601-610. doi: 10.1089/AID.2021.0038. Epub 2021 Oct 18. AIDS Res Hum Retroviruses. 2022. PMID: 34544269 Free PMC article.
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