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In vivo dynamics and anti-tumor effects of EpCAM-directed CAR T-cells against brain metastases from lung cancer.
Xu T, Karschnia P, Cadilha BL, Dede S, Lorenz M, Seewaldt N, Nikolaishvili E, Müller K, Blobner J, Teske N, Herold JJ, Rejeski K, Langer S, Obeck H, Lorenzini T, Mulazzani M, Zhang W, Ishikawa-Ankerhold H, Buchholz VR, Subklewe M, Thon N, Straube A, Tonn JC, Kobold S, von Baumgarten L. Xu T, et al. Among authors: buchholz vr. Oncoimmunology. 2023 Jan 13;12(1):2163781. doi: 10.1080/2162402X.2022.2163781. eCollection 2023. Oncoimmunology. 2023. PMID: 36687005 Free PMC article.
Differential antigen processing by dendritic cell subsets in vivo.
Dudziak D, Kamphorst AO, Heidkamp GF, Buchholz VR, Trumpfheller C, Yamazaki S, Cheong C, Liu K, Lee HW, Park CG, Steinman RM, Nussenzweig MC. Dudziak D, et al. Among authors: buchholz vr. Science. 2007 Jan 5;315(5808):107-11. doi: 10.1126/science.1136080. Science. 2007. PMID: 17204652 Free article.
Long-term in vivo microscopy of CAR T cell dynamics during eradication of CNS lymphoma in mice.
Mulazzani M, Fräßle SP, von Mücke-Heim I, Langer S, Zhou X, Ishikawa-Ankerhold H, Leube J, Zhang W, Dötsch S, Svec M, Rudelius M, Dreyling M, von Bergwelt-Baildon M, Straube A, Buchholz VR, Busch DH, von Baumgarten L. Mulazzani M, et al. Among authors: buchholz vr. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24275-24284. doi: 10.1073/pnas.1903854116. Epub 2019 Nov 11. Proc Natl Acad Sci U S A. 2019. PMID: 31712432 Free PMC article.
Role of memory T cell subsets for adoptive immunotherapy.
Busch DH, Fräßle SP, Sommermeyer D, Buchholz VR, Riddell SR. Busch DH, et al. Among authors: buchholz vr. Semin Immunol. 2016 Feb;28(1):28-34. doi: 10.1016/j.smim.2016.02.001. Epub 2016 Mar 11. Semin Immunol. 2016. PMID: 26976826 Free PMC article. Review.
Reverse TCR repertoire evolution toward dominant low-affinity clones during chronic CMV infection.
Schober K, Voit F, Grassmann S, Müller TR, Eggert J, Jarosch S, Weißbrich B, Hoffmann P, Borkner L, Nio E, Fanchi L, Clouser CR, Radhakrishnan A, Mihatsch L, Lückemeier P, Leube J, Dössinger G, Klein L, Neuenhahn M, Oduro JD, Cicin-Sain L, Buchholz VR, Busch DH. Schober K, et al. Among authors: buchholz vr. Nat Immunol. 2020 Apr;21(4):434-441. doi: 10.1038/s41590-020-0628-2. Epub 2020 Mar 16. Nat Immunol. 2020. PMID: 32205883
T cell memories of past divisions.
Kretschmer L, Buchholz VR. Kretschmer L, et al. Among authors: buchholz vr. Nat Immunol. 2022 May;23(5):646-647. doi: 10.1038/s41590-022-01193-3. Nat Immunol. 2022. PMID: 35449418 No abstract available.
Signatures of recent activation identify a circulating T cell compartment containing tumor-specific antigen receptors with high avidity.
Purcarea A, Jarosch S, Barton J, Grassmann S, Pachmayr L, D'Ippolito E, Hammel M, Hochholzer A, Wagner KI, van den Berg JH, Buchholz VR, Haanen JBAG, Busch DH, Schober K. Purcarea A, et al. Among authors: buchholz vr. Sci Immunol. 2022 Aug 12;7(74):eabm2077. doi: 10.1126/sciimmunol.abm2077. Epub 2022 Aug 12. Sci Immunol. 2022. PMID: 35960818
PGE2 limits effector expansion of tumour-infiltrating stem-like CD8+ T cells.
Lacher SB, Dörr J, de Almeida GP, Hönninger J, Bayerl F, Hirschberger A, Pedde AM, Meiser P, Ramsauer L, Rudolph TJ, Spranger N, Morotti M, Grimm AJ, Jarosch S, Oner A, Gregor L, Lesch S, Michaelides S, Fertig L, Briukhovetska D, Majed L, Stock S, Busch DH, Buchholz VR, Knolle PA, Zehn D, Dangaj Laniti D, Kobold S, Böttcher JP. Lacher SB, et al. Among authors: buchholz vr. Nature. 2024 Apr 24. doi: 10.1038/s41586-024-07254-x. Online ahead of print. Nature. 2024. PMID: 38658748
46 results