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AAV vectors displaying bispecific DARPins enable dual-control targeted gene delivery.
Theuerkauf SA, Herrera-Carrillo E, John F, Zinser LJ, Molina MA, Riechert V, Thalheimer FB, Börner K, Grimm D, Chlanda P, Berkhout B, Buchholz CJ. Theuerkauf SA, et al. Among authors: buchholz cj. Biomaterials. 2023 Dec;303:122399. doi: 10.1016/j.biomaterials.2023.122399. Epub 2023 Nov 16. Biomaterials. 2023. PMID: 37992599 Free article.
A Library-Based Screening Strategy for the Identification of DARPins as Ligands for Receptor-Targeted AAV and Lentiviral Vectors.
Hartmann J, Münch RC, Freiling RT, Schneider IC, Dreier B, Samukange W, Koch J, Seeger MA, Plückthun A, Buchholz CJ. Hartmann J, et al. Among authors: buchholz cj. Mol Ther Methods Clin Dev. 2018 Jul 6;10:128-143. doi: 10.1016/j.omtm.2018.07.001. eCollection 2018 Sep 21. Mol Ther Methods Clin Dev. 2018. PMID: 30101151 Free PMC article.
GluA4-Targeted AAV Vectors Deliver Genes Selectively to Interneurons while Relying on the AAV Receptor for Entry.
Hartmann J, Thalheimer FB, Höpfner F, Kerzel T, Khodosevich K, García-González D, Monyer H, Diester I, Büning H, Carette JE, Fries P, Buchholz CJ. Hartmann J, et al. Among authors: buchholz cj. Mol Ther Methods Clin Dev. 2019 Jul 23;14:252-260. doi: 10.1016/j.omtm.2019.07.004. eCollection 2019 Sep 13. Mol Ther Methods Clin Dev. 2019. PMID: 31463334 Free PMC article.
In vivo generated human CAR T cells eradicate tumor cells.
Agarwal S, Weidner T, Thalheimer FB, Buchholz CJ. Agarwal S, et al. Among authors: buchholz cj. Oncoimmunology. 2019 Oct 10;8(12):e1671761. doi: 10.1080/2162402X.2019.1671761. eCollection 2019. Oncoimmunology. 2019. PMID: 31741773 Free PMC article.
In Vivo Generation of CAR T Cells Selectively in Human CD4+ Lymphocytes.
Agarwal S, Hanauer JDS, Frank AM, Riechert V, Thalheimer FB, Buchholz CJ. Agarwal S, et al. Among authors: buchholz cj. Mol Ther. 2020 Aug 5;28(8):1783-1794. doi: 10.1016/j.ymthe.2020.05.005. Epub 2020 May 16. Mol Ther. 2020. PMID: 32485137 Free PMC article.
134 results