Brzovic PS - Search Results

1

Crucial roles of the BRCA1-BARD1 E3 ubiquitin ligase activity in homology-directed DNA repair.

Wang M, Li W, Tomimatsu N, Yu CH, Ji JH, Alejo S, Witus SR, Alimbetov D, Fitzgerald O, Wu B, Wang Q, Huang Y, Gan Y, Dong F, Kwon Y, Sareddy GR, Curiel TJ, Habib AA, Hromas R, Dos Santos Passos C, Yao T, Ivanov DN, Brzovic PS, Burma S, Klevit RE, Zhao W. Wang M, et al. Among authors: brzovic ps. Mol Cell. 2023 Oct 19;83(20):3679-3691.e8. doi: 10.1016/j.molcel.2023.09.015. Epub 2023 Oct 4. Mol Cell. 2023. PMID: 37797621

2

Calcium-dependent solvation of the myristoyl group of recoverin.

Hughes RE, Brzovic PS, Klevit RE, Hurley JB. Hughes RE, et al. Among authors: brzovic ps. Biochemistry. 1995 Sep 12;34(36):11410-6. doi: 10.1021/bi00036a013. Biochemistry. 1995. PMID: 7547868

3

The cancer-predisposing mutation C61G disrupts homodimer formation in the NH2-terminal BRCA1 RING finger domain.

Brzovic PS, Meza J, King MC, Klevit RE. Brzovic PS, et al. J Biol Chem. 1998 Apr 3;273(14):7795-9. doi: 10.1074/jbc.273.14.7795. J Biol Chem. 1998. PMID: 9525870 Free article.

4

Ca2+-dependent conformational changes in bovine GCAP-2.

Hughes RE, Brzovic PS, Dizhoor AM, Klevit RE, Hurley JB. Hughes RE, et al. Among authors: brzovic ps. Protein Sci. 1998 Dec;7(12):2675-80. doi: 10.1002/pro.5560071222. Protein Sci. 1998. PMID: 9865963 Free PMC article.

5

Mapping the functional domains of BRCA1. Interaction of the ring finger domains of BRCA1 and BARD1.

Meza JE, Brzovic PS, King MC, Klevit RE. Meza JE, et al. Among authors: brzovic ps. J Biol Chem. 1999 Feb 26;274(9):5659-65. doi: 10.1074/jbc.274.9.5659. J Biol Chem. 1999. PMID: 10026184 Free article.

6

BRCA1 RING domain cancer-predisposing mutations. Structural consequences and effects on protein-protein interactions.

Brzovic PS, Meza JE, King MC, Klevit RE. Brzovic PS, et al. J Biol Chem. 2001 Nov 2;276(44):41399-406. doi: 10.1074/jbc.M106551200. Epub 2001 Aug 28. J Biol Chem. 2001. PMID: 11526114 Free article.

7

Structure of a BRCA1-BARD1 heterodimeric RING-RING complex.

Brzovic PS, Rajagopal P, Hoyt DW, King MC, Klevit RE. Brzovic PS, et al. Nat Struct Biol. 2001 Oct;8(10):833-7. doi: 10.1038/nsb1001-833. Nat Struct Biol. 2001. PMID: 11573085

8

Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex.

Brzovic PS, Keeffe JR, Nishikawa H, Miyamoto K, Fox D 3rd, Fukuda M, Ohta T, Klevit R. Brzovic PS, et al. Proc Natl Acad Sci U S A. 2003 May 13;100(10):5646-51. doi: 10.1073/pnas.0836054100. Epub 2003 May 5. Proc Natl Acad Sci U S A. 2003. PMID: 12732733 Free PMC article.

9

A UbcH5/ubiquitin noncovalent complex is required for processive BRCA1-directed ubiquitination.

Brzovic PS, Lissounov A, Christensen DE, Hoyt DW, Klevit RE. Brzovic PS, et al. Mol Cell. 2006 Mar 17;21(6):873-80. doi: 10.1016/j.molcel.2006.02.008. Mol Cell. 2006. PMID: 16543155 Free article.

10

Ubiquitin transfer from the E2 perspective: why is UbcH5 so promiscuous?

Brzovic PS, Klevit RE. Brzovic PS, et al. Cell Cycle. 2006 Dec;5(24):2867-73. doi: 10.4161/cc.5.24.3592. Epub 2006 Dec 8. Cell Cycle. 2006. PMID: 17218787

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