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OATD-02 Validates the Benefits of Pharmacological Inhibition of Arginase 1 and 2 in Cancer.
Grzybowski MM, Stańczak PS, Pomper P, Błaszczyk R, Borek B, Gzik A, Nowicka J, Jędrzejczak K, Brzezińska J, Rejczak T, Güner-Chalimoniuk NC, Kikulska A, Mlącki M, Pęczkowicz-Szyszka J, Olczak J, Gołębiowski A, Dzwonek K, Dobrzański P, Zasłona Z. Grzybowski MM, et al. Among authors: brzezinska j. Cancers (Basel). 2022 Aug 17;14(16):3967. doi: 10.3390/cancers14163967. Cancers (Basel). 2022. PMID: 36010962 Free PMC article.
Arginase 1/2 Inhibitor OATD-02: From Discovery to First-in-man Setup in Cancer Immunotherapy.
Borek B, Nowicka J, Gzik A, Dziegielewski M, Jedrzejczak K, Brzezinska J, Grzybowski M, Stanczak P, Pomper P, Zagozdzon A, Rejczak T, Matyszewski K, Golebiowski A, Olczak J, Lisiecki K, Tyszkiewicz M, Kania M, Piasecka S, Cabaj A, Dera P, Mulewski K, Chrzanowski J, Kusmirek D, Sobolewska E, Magdycz M, Mucha L, Masnyk M, Golab J, Nowotny M, Nowak E, Napiorkowska-Gromadzka A, Pikul S, Jazwiec R, Dzwonek K, Dobrzanski P, Meyring M, Skowronek K, Iwanowski P, Zaslona Z, Blaszczyk R. Borek B, et al. Among authors: brzezinska j. Mol Cancer Ther. 2023 Jul 5;22(7):807-817. doi: 10.1158/1535-7163.MCT-22-0721. Mol Cancer Ther. 2023. PMID: 36939275
Novel orally bioavailable piperidine derivatives as extracellular arginase inhibitors developed by a ring expansion.
Gzik A, Borek B, Chrzanowski J, Jedrzejczak K, Dziegielewski M, Brzezinska J, Nowicka J, Grzybowski MM, Rejczak T, Niedzialek D, Wieczorek G, Olczak J, Golebiowski A, Zaslona Z, Blaszczyk R. Gzik A, et al. Among authors: brzezinska j. Eur J Med Chem. 2024 Jan 15;264:116033. doi: 10.1016/j.ejmech.2023.116033. Epub 2023 Dec 10. Eur J Med Chem. 2024. PMID: 38096651
Severity of Omicron (B.1.1.529) and Delta (B.1.617.2) SARS-CoV-2 infection among hospitalised adults: A prospective cohort study in Bristol, United Kingdom.
Hyams C, Challen R, Marlow R, Nguyen J, Begier E, Southern J, King J, Morley A, Kinney J, Clout M, Oliver J, Gray S, Ellsbury G, Maskell N, Jodar L, Gessner B, McLaughlin J, Danon L, Finn A; AvonCAP Research Group. Hyams C, et al. Lancet Reg Health Eur. 2023 Feb;25:100556. doi: 10.1016/j.lanepe.2022.100556. Epub 2022 Dec 12. Lancet Reg Health Eur. 2023. PMID: 36530491 Free PMC article.
Effectiveness of BNT162b2 COVID-19 vaccination in prevention of hospitalisations and severe disease in adults with SARS-CoV-2 Delta (B.1.617.2) and Omicron (B.1.1.529) variant between June 2021 and July 2022: A prospective test negative case-control study.
Chatzilena A, Hyams C, Challen R, Marlow R, King J, Adegbite D, Kinney J, Clout M, Maskell N, Oliver J, Danon L, Finn A; Avon CAP Research Group. Chatzilena A, et al. Lancet Reg Health Eur. 2022 Dec 7;25:100552. doi: 10.1016/j.lanepe.2022.100552. eCollection 2023 Feb. Lancet Reg Health Eur. 2022. PMID: 36506791 Free PMC article.
28 results