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A mechanism for the extension and unfolding of parallel telomeric G-quadruplexes by human telomerase at single-molecule resolution.
Paudel BP, Moye AL, Abou Assi H, El-Khoury R, Cohen SB, Holien JK, Birrento ML, Samosorn S, Intharapichai K, Tomlinson CG, Teulade-Fichou MP, González C, Beck JL, Damha MJ, van Oijen AM, Bryan TM. Paudel BP, et al. Among authors: bryan tm. Elife. 2020 Jul 29;9:e56428. doi: 10.7554/eLife.56428. Elife. 2020. PMID: 32723475 Free PMC article.
I-motif DNA structures are formed in the nuclei of human cells.
Zeraati M, Langley DB, Schofield P, Moye AL, Rouet R, Hughes WE, Bryan TM, Dinger ME, Christ D. Zeraati M, et al. Among authors: bryan tm. Nat Chem. 2018 Jun;10(6):631-637. doi: 10.1038/s41557-018-0046-3. Epub 2018 Apr 23. Nat Chem. 2018. PMID: 29686376
Multiple DNA-binding sites in Tetrahymena telomerase.
Finger SN, Bryan TM. Finger SN, et al. Among authors: bryan tm. Nucleic Acids Res. 2008 Mar;36(4):1260-72. doi: 10.1093/nar/gkm866. Epub 2008 Jan 3. Nucleic Acids Res. 2008. PMID: 18174223 Free PMC article.
Direct involvement of the TEN domain at the active site of human telomerase.
Jurczyluk J, Nouwens AS, Holien JK, Adams TE, Lovrecz GO, Parker MW, Cohen SB, Bryan TM. Jurczyluk J, et al. Among authors: bryan tm. Nucleic Acids Res. 2011 Mar;39(5):1774-88. doi: 10.1093/nar/gkq1083. Epub 2010 Nov 3. Nucleic Acids Res. 2011. PMID: 21051362 Free PMC article.
Human RTEL1 stabilizes long G-overhangs allowing telomerase-dependent over-extension.
Porreca RM, Glousker G, Awad A, Matilla Fernandez MI, Gibaud A, Naucke C, Cohen SB, Bryan TM, Tzfati Y, Draskovic I, Londoño-Vallejo A. Porreca RM, et al. Among authors: bryan tm. Nucleic Acids Res. 2018 May 18;46(9):4533-4545. doi: 10.1093/nar/gky173. Nucleic Acids Res. 2018. PMID: 29522136 Free PMC article.
Extension of G-quadruplex DNA by ciliate telomerase.
Oganesian L, Moon IK, Bryan TM, Jarstfer MB. Oganesian L, et al. Among authors: bryan tm. EMBO J. 2006 Mar 8;25(5):1148-59. doi: 10.1038/sj.emboj.7601006. Epub 2006 Mar 2. EMBO J. 2006. PMID: 16511573 Free PMC article.
66 results