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Understanding the molecular basis of toxin promiscuity: the analgesic sea anemone peptide APETx2 interacts with acid-sensing ion channel 3 and hERG channels via overlapping pharmacophores.
Jensen JE, Cristofori-Armstrong B, Anangi R, Rosengren KJ, Lau CH, Mobli M, Brust A, Alewood PF, King GF, Rash LD. Jensen JE, et al. Among authors: brust a. J Med Chem. 2014 Nov 13;57(21):9195-203. doi: 10.1021/jm501400p. Epub 2014 Nov 4. J Med Chem. 2014. PMID: 25337890
The Snake with the Scorpion's Sting: Novel Three-Finger Toxin Sodium Channel Activators from the Venom of the Long-Glanded Blue Coral Snake (Calliophis bivirgatus).
Yang DC, Deuis JR, Dashevsky D, Dobson J, Jackson TN, Brust A, Xie B, Koludarov I, Debono J, Hendrikx I, Hodgson WC, Josh P, Nouwens A, Baillie GJ, Bruxner TJ, Alewood PF, Lim KK, Frank N, Vetter I, Fry BG. Yang DC, et al. Among authors: brust a. Toxins (Basel). 2016 Oct 18;8(10):303. doi: 10.3390/toxins8100303. Toxins (Basel). 2016. PMID: 27763551 Free PMC article.
Differential evolution and neofunctionalization of snake venom metalloprotease domains.
Brust A, Sunagar K, Undheim EA, Vetter I, Yang DC, Casewell NR, Jackson TN, Koludarov I, Alewood PF, Hodgson WC, Lewis RJ, King GF, Antunes A, Hendrikx I, Fry BG. Brust A, et al. Mol Cell Proteomics. 2013 Mar;12(3):651-63. doi: 10.1074/mcp.M112.023135. Epub 2012 Dec 12. Mol Cell Proteomics. 2013. PMID: 23242553 Free PMC article.
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