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Disrupted Cacna1c gene expression perturbs spontaneous Ca2+ activity causing abnormal brain development and increased anxiety.
Smedler E, Louhivuori L, Romanov RA, Masini D, Dehnisch Ellström I, Wang C, Caramia M, West Z, Zhang S, Rebellato P, Malmersjö S, Brusini I, Kanatani S, Fisone G, Harkany T, Uhlén P. Smedler E, et al. Among authors: brusini i. Proc Natl Acad Sci U S A. 2022 Feb 15;119(7):e2108768119. doi: 10.1073/pnas.2108768119. Proc Natl Acad Sci U S A. 2022. PMID: 35135875 Free PMC article.
Changes in brain architecture are consistent with altered fear processing in domestic rabbits.
Brusini I, Carneiro M, Wang C, Rubin CJ, Ring H, Afonso S, Blanco-Aguiar JA, Ferrand N, Rafati N, Villafuerte R, Smedby Ö, Damberg P, Hallböök F, Fredrikson M, Andersson L. Brusini I, et al. Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):7380-7385. doi: 10.1073/pnas.1801024115. Epub 2018 Jun 25. Proc Natl Acad Sci U S A. 2018. PMID: 29941556 Free PMC article.
Age-Specific Adult Rat Brain MRI Templates and Tissue Probability Maps.
MacNicol E, Wright P, Kim E, Brusini I, Esteban O, Simmons C, Turkheimer FE, Cash D. MacNicol E, et al. Among authors: brusini i. Front Neuroinform. 2022 Jan 7;15:669049. doi: 10.3389/fninf.2021.669049. eCollection 2021. Front Neuroinform. 2022. PMID: 35069163 Free PMC article.
The humanised CYP2C19 transgenic mouse exhibits cerebellar atrophy and movement impairment reminiscent of ataxia.
Milosavljević F, Brusini I, Atanasov A, Manojlović M, Vučić M, Oreščanin-Dušić Z, Brkljačić J, Miljević Č, Nikolić-Kokić A, Blagojević D, Wang C, Damberg P, Pešić V, Tyndale RF, Ingelman-Sundberg M, Jukić MM. Milosavljević F, et al. Among authors: brusini i. Neuropathol Appl Neurobiol. 2023 Feb;49(1):e12867. doi: 10.1111/nan.12867. Neuropathol Appl Neurobiol. 2023. PMID: 36536486 Free PMC article.