Brunner T - Search Results

1

Natural Merosesquiterpenes Activate the DNA Damage Response via DNA Strand Break Formation and Trigger Apoptotic Cell Death in p53-Wild-type and Mutant Colorectal Cancer.

Jiso A, Demuth P, Bachowsky M, Haas M, Seiwert N, Heylmann D, Rasenberger B, Christmann M, Dietrich L, Brunner T, Riyanti, Schäberle TF, Plubrukarn A, Fahrer J. Jiso A, et al. Among authors: brunner t. Cancers (Basel). 2021 Jun 30;13(13):3282. doi: 10.3390/cancers13133282. Cancers (Basel). 2021. PMID: 34209047 Free PMC article.

2

Thiazolides promote G1 cell cycle arrest in colorectal cancer cells by targeting the mitochondrial respiratory chain.

Ripani P, Delp J, Bode K, Delgado ME, Dietrich L, Betzler VM, Yan N, von Scheven G, Mayer TU, Leist M, Brunner T. Ripani P, et al. Among authors: brunner t. Oncogene. 2020 Mar;39(11):2345-2357. doi: 10.1038/s41388-019-1142-6. Epub 2019 Dec 16. Oncogene. 2020. PMID: 31844249

3

Heme oxygenase 1 protects human colonocytes against ROS formation, oxidative DNA damage and cytotoxicity induced by heme iron, but not inorganic iron.

Seiwert N, Wecklein S, Demuth P, Hasselwander S, Kemper TA, Schwerdtle T, Brunner T, Fahrer J. Seiwert N, et al. Among authors: brunner t. Cell Death Dis. 2020 Sep 23;11(9):787. doi: 10.1038/s41419-020-02950-8. Cell Death Dis. 2020. PMID: 32968051 Free PMC article.

4

The Mitochondrial Disruptor Devimistat (CPI-613) Synergizes with Genotoxic Anticancer Drugs in Colorectal Cancer Therapy in a Bim-Dependent Manner.

Arnold C, Demuth P, Seiwert N, Wittmann S, Boengler K, Rasenberger B, Christmann M, Huber M, Brunner T, Linnebacher M, Fahrer J. Arnold C, et al. Among authors: brunner t. Mol Cancer Ther. 2022 Jan;21(1):100-112. doi: 10.1158/1535-7163.MCT-21-0393. Epub 2021 Nov 8. Mol Cancer Ther. 2022. PMID: 34750196

5

The orphan nuclear receptor LRH-1/NR5a2 critically regulates T cell functions.

Seitz C, Huang J, Geiselhöringer AL, Galbani-Bianchi P, Michalek S, Phan TS, Reinhold C, Dietrich L, Schmidt C, Corazza N, Delgado E, Schnalzger T, Schoonjans K, Brunner T. Seitz C, et al. Among authors: brunner t. Sci Adv. 2019 Jul 17;5(7):eaav9732. doi: 10.1126/sciadv.aav9732. eCollection 2019 Jul. Sci Adv. 2019. PMID: 31328159 Free PMC article.

6

Immune escape of colorectal tumours via local LRH-1/Cyp11b1-mediated synthesis of immunosuppressive glucocorticoids.

Ahmed A, Reinhold C, Breunig E, Phan TS, Dietrich L, Kostadinova F, Urwyler C, Merk VM, Noti M, Toja da Silva I, Bode K, Nahle F, Plazzo AP, Koerner J, Stuber R, Menche C, Karamitopoulou E, Farin HF, Gollob KJ, Brunner T. Ahmed A, et al. Among authors: brunner t. Mol Oncol. 2023 Aug;17(8):1545-1566. doi: 10.1002/1878-0261.13414. Epub 2023 Mar 9. Mol Oncol. 2023. PMID: 36861295 Free PMC article.

7

Structure-function relationship of thiazolide-induced apoptosis in colorectal tumor cells.

Brockmann A, Strittmatter T, May S, Stemmer K, Marx A, Brunner T. Brockmann A, et al. Among authors: brunner t. ACS Chem Biol. 2014 Jul 18;9(7):1520-7. doi: 10.1021/cb500209a. Epub 2014 May 20. ACS Chem Biol. 2014. PMID: 24810314

8

Death Receptor Interactions With the Mitochondrial Cell Death Pathway During Immune Cell-, Drug- and Toxin-Induced Liver Damage.

Spinnenhirn V, Demgenski J, Brunner T. Spinnenhirn V, et al. Among authors: brunner t. Front Cell Dev Biol. 2019 Apr 24;7:72. doi: 10.3389/fcell.2019.00072. eCollection 2019. Front Cell Dev Biol. 2019. PMID: 31069226 Free PMC article. Review.

9

Thiazolides promote apoptosis in colorectal tumor cells via MAP kinase-induced Bim and Puma activation.

Brockmann A, Bluwstein A, Kögel A, May S, Marx A, Tschan MP, Brunner T. Brockmann A, et al. Among authors: brunner t. Cell Death Dis. 2015 Jun 4;6(6):e1778. doi: 10.1038/cddis.2015.137. Cell Death Dis. 2015. PMID: 26043078 Free PMC article.

10

Cell death at the intestinal epithelial front line.

Delgado ME, Grabinger T, Brunner T. Delgado ME, et al. Among authors: brunner t. FEBS J. 2016 Jul;283(14):2701-19. doi: 10.1111/febs.13575. Epub 2015 Nov 11. FEBS J. 2016. PMID: 26499289 Free article. Review.

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