Brunner T - Search Results

1

Heme oxygenase 1 protects human colonocytes against ROS formation, oxidative DNA damage and cytotoxicity induced by heme iron, but not inorganic iron.

Seiwert N, Wecklein S, Demuth P, Hasselwander S, Kemper TA, Schwerdtle T, Brunner T, Fahrer J. Seiwert N, et al. Among authors: brunner t. Cell Death Dis. 2020 Sep 23;11(9):787. doi: 10.1038/s41419-020-02950-8. Cell Death Dis. 2020. PMID: 32968051 Free PMC article.

2

Thiazolides promote apoptosis in colorectal tumor cells via MAP kinase-induced Bim and Puma activation.

Brockmann A, Bluwstein A, Kögel A, May S, Marx A, Tschan MP, Brunner T. Brockmann A, et al. Among authors: brunner t. Cell Death Dis. 2015 Jun 4;6(6):e1778. doi: 10.1038/cddis.2015.137. Cell Death Dis. 2015. PMID: 26043078 Free PMC article.

3

Liver receptor homolog-1 (NR5a2) regulates CD95/Fas ligand transcription and associated T-cell effector functions.

Schwaderer J, Gaiser AK, Phan TS, Delgado ME, Brunner T. Schwaderer J, et al. Among authors: brunner t. Cell Death Dis. 2017 Apr 13;8(4):e2745. doi: 10.1038/cddis.2017.173. Cell Death Dis. 2017. PMID: 28406481 Free PMC article.

4

Pharmacological LRH-1/Nr5a2 inhibition limits pro-inflammatory cytokine production in macrophages and associated experimental hepatitis.

Schwaderer J, Phan TS, Glöckner A, Delp J, Leist M, Brunner T, Delgado ME. Schwaderer J, et al. Among authors: brunner t. Cell Death Dis. 2020 Feb 28;11(2):154. doi: 10.1038/s41419-020-2348-9. Cell Death Dis. 2020. PMID: 32111818 Free PMC article.

5

Natural Merosesquiterpenes Activate the DNA Damage Response via DNA Strand Break Formation and Trigger Apoptotic Cell Death in p53-Wild-type and Mutant Colorectal Cancer.

Jiso A, Demuth P, Bachowsky M, Haas M, Seiwert N, Heylmann D, Rasenberger B, Christmann M, Dietrich L, Brunner T, Riyanti, Schäberle TF, Plubrukarn A, Fahrer J. Jiso A, et al. Among authors: brunner t. Cancers (Basel). 2021 Jun 30;13(13):3282. doi: 10.3390/cancers13133282. Cancers (Basel). 2021. PMID: 34209047 Free PMC article.

6

The Mitochondrial Disruptor Devimistat (CPI-613) Synergizes with Genotoxic Anticancer Drugs in Colorectal Cancer Therapy in a Bim-Dependent Manner.

Arnold C, Demuth P, Seiwert N, Wittmann S, Boengler K, Rasenberger B, Christmann M, Huber M, Brunner T, Linnebacher M, Fahrer J. Arnold C, et al. Among authors: brunner t. Mol Cancer Ther. 2022 Jan;21(1):100-112. doi: 10.1158/1535-7163.MCT-21-0393. Epub 2021 Nov 8. Mol Cancer Ther. 2022. PMID: 34750196

7

Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP(+).

Krug AK, Gutbier S, Zhao L, Pöltl D, Kullmann C, Ivanova V, Förster S, Jagtap S, Meiser J, Leparc G, Schildknecht S, Adam M, Hiller K, Farhan H, Brunner T, Hartung T, Sachinidis A, Leist M. Krug AK, et al. Among authors: brunner t. Cell Death Dis. 2014 May 8;5(5):e1222. doi: 10.1038/cddis.2014.166. Cell Death Dis. 2014. PMID: 24810058 Free PMC article.

8

Ex vivo culture of intestinal crypt organoids as a model system for assessing cell death induction in intestinal epithelial cells and enteropathy.

Grabinger T, Luks L, Kostadinova F, Zimberlin C, Medema JP, Leist M, Brunner T. Grabinger T, et al. Among authors: brunner t. Cell Death Dis. 2014 May 15;5(5):e1228. doi: 10.1038/cddis.2014.183. Cell Death Dis. 2014. PMID: 24832600 Free PMC article.

9

Prevention of neuronal apoptosis by astrocytes through thiol-mediated stress response modulation and accelerated recovery from proteotoxic stress.

Gutbier S, Spreng AS, Delp J, Schildknecht S, Karreman C, Suciu I, Brunner T, Groettrup M, Leist M. Gutbier S, et al. Among authors: brunner t. Cell Death Differ. 2018 Dec;25(12):2101-2117. doi: 10.1038/s41418-018-0229-x. Epub 2018 Nov 2. Cell Death Differ. 2018. PMID: 30390092 Free PMC article.

10

Non-canonical BIM-regulated energy metabolism determines drug-induced liver necrosis.

Lambrecht R, Rudolf F, Ückert AK, Sladky VC, Phan TS, Jansen J, Naim S, Kaufmann T, Keogh A, Kirschnek S, Mangerich A, Stengel F, Leist M, Villunger A, Brunner T. Lambrecht R, et al. Among authors: brunner t. Cell Death Differ. 2024 Jan;31(1):119-131. doi: 10.1038/s41418-023-01245-7. Epub 2023 Nov 24. Cell Death Differ. 2024. PMID: 38001256 Free PMC article.

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