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Utility of the RIG-I Agonist Triphosphate RNA for Melanoma Therapy.
Helms MW, Jahn-Hofmann K, Gnerlich F, Metz-Weidmann C, Braun M, Dietert G, Scherer P, Grandien K, Theilhaber J, Cao H, Wagenaar TR, Schnurr MM, Endres S, Wiederschain D, Scheidler S, Rothenfußer S, Brunner B, König LM. Helms MW, et al. Among authors: brunner b. Mol Cancer Ther. 2019 Dec;18(12):2343-2356. doi: 10.1158/1535-7163.MCT-18-1262. Epub 2019 Sep 12. Mol Cancer Ther. 2019. PMID: 31515294
Nanobody-siRNA Conjugates for Targeted Delivery of siRNA to Cancer Cells.
Zavoiura O, Brunner B, Casteels P, Zimmermann L, Ozog M, Boutton C, Helms MW, Wagenaar T, Adam V, Peterka J, Metz-Weidmann C, Deschaght P, Scheidler S, Jahn-Hofmann K. Zavoiura O, et al. Among authors: brunner b. Mol Pharm. 2021 Mar 1;18(3):1048-1060. doi: 10.1021/acs.molpharmaceut.0c01001. Epub 2021 Jan 14. Mol Pharm. 2021. PMID: 33444501
Liver-Specific Knockdown of Class IIa HDACs Has Limited Efficacy on Glucose Metabolism but Entails Severe Organ Side Effects in Mice.
Ziegler N, Raichur S, Brunner B, Hemmann U, Stolte M, Schwahn U, Prochnow HP, Metz-Weidmann C, Tennagels N, Margerie D, Wohlfart P, Bielohuby M. Ziegler N, et al. Among authors: brunner b. Front Endocrinol (Lausanne). 2020 Aug 28;11:598. doi: 10.3389/fendo.2020.00598. eCollection 2020. Front Endocrinol (Lausanne). 2020. PMID: 32982982 Free PMC article.
Inhibition of citrate cotransporter Slc13a5/mINDY by RNAi improves hepatic insulin sensitivity and prevents diet-induced non-alcoholic fatty liver disease in mice.
Brachs S, Winkel AF, Tang H, Birkenfeld AL, Brunner B, Jahn-Hofmann K, Margerie D, Ruetten H, Schmoll D, Spranger J. Brachs S, et al. Among authors: brunner b. Mol Metab. 2016 Aug 13;5(11):1072-1082. doi: 10.1016/j.molmet.2016.08.004. eCollection 2016 Nov. Mol Metab. 2016. PMID: 27818933 Free PMC article.
150 results