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Dysregulation of lysophosphatidic acids in multiple sclerosis and autoimmune encephalomyelitis.
Schmitz K, Brunkhorst R, de Bruin N, Mayer CA, Häussler A, Ferreiros N, Schiffmann S, Parnham MJ, Tunaru S, Chun J, Offermanns S, Foerch C, Scholich K, Vogt J, Wicker S, Lötsch J, Geisslinger G, Tegeder I. Schmitz K, et al. Among authors: brunkhorst r. Acta Neuropathol Commun. 2017 Jun 2;5(1):42. doi: 10.1186/s40478-017-0446-4. Acta Neuropathol Commun. 2017. PMID: 28578681 Free PMC article.
Preanalytical Biases in the Measurement of Human Blood Sphingolipids.
Brunkhorst R, Pfeilschifter W, Patyna S, Büttner S, Eckes T, Trautmann S, Thomas D, Pfeilschifter J, Koch A. Brunkhorst R, et al. Int J Mol Sci. 2018 May 7;19(5):1390. doi: 10.3390/ijms19051390. Int J Mol Sci. 2018. PMID: 29735920 Free PMC article.
The relevance of ceramides and their synthesizing enzymes for multiple sclerosis.
Kurz J, Brunkhorst R, Foerch C, Blum L, Henke M, Gabriel L, Ulshöfer T, Ferreirós N, Parnham MJ, Geisslinger G, Schiffmann S. Kurz J, et al. Among authors: brunkhorst r. Clin Sci (Lond). 2018 Aug 17;132(17):1963-1976. doi: 10.1042/CS20180506. Print 2018 Sep 14. Clin Sci (Lond). 2018. PMID: 30219773
Diurnal regulation of sphingolipids in blood.
Brunkhorst R, Pfeilschifter W, Rajkovic N, Pfeffer M, Fischer C, Korf HW, Christoffersen C, Trautmann S, Thomas D, Pfeilschifter J, Koch A. Brunkhorst R, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Mar;1864(3):304-311. doi: 10.1016/j.bbalip.2018.12.001. Epub 2018 Dec 15. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 30557628
S1P d20:1, an endogenous modulator of S1P d18:1/S1P2 -dependent signaling.
Vutukuri R, Koch A, Trautmann S, Schreiber Y, Thomas D, Mayser F, Meyer Zu Heringdorf D, Pfeilschifter J, Pfeilschifter W, Brunkhorst R. Vutukuri R, et al. Among authors: brunkhorst r. FASEB J. 2020 Mar;34(3):3932-3942. doi: 10.1096/fj.201902391R. Epub 2020 Jan 15. FASEB J. 2020. PMID: 31944406
Sapropterin (BH4) Aggravates Autoimmune Encephalomyelitis in Mice.
Schmitz K, Trautmann S, Hahnefeld L, Fischer C, Schreiber Y, Wilken-Schmitz A, Gurke R, Brunkhorst R, Werner ER, Watschinger K, Wicker S, Thomas D, Geisslinger G, Tegeder I. Schmitz K, et al. Among authors: brunkhorst r. Neurotherapeutics. 2021 Jul;18(3):1862-1879. doi: 10.1007/s13311-021-01043-4. Epub 2021 Apr 12. Neurotherapeutics. 2021. PMID: 33844153 Free PMC article.
190 results