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Complete neural stem cell (NSC) neuronal differentiation requires a branched chain amino acids-induced persistent metabolic shift towards energy metabolism.
Bifari F, Dolci S, Bottani E, Pino A, Di Chio M, Zorzin S, Ragni M, Zamfir RG, Brunetti D, Bardelli D, Delfino P, Cattaneo MG, Bordo R, Tedesco L, Rossi F, Bossolasco P, Corbo V, Fumagalli G, Nisoli E, Valerio A, Decimo I. Bifari F, et al. Among authors: brunetti d. Pharmacol Res. 2020 Aug;158:104863. doi: 10.1016/j.phrs.2020.104863. Epub 2020 May 12. Pharmacol Res. 2020. PMID: 32407957 Free article.
Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome.
Inak G, Rybak-Wolf A, Lisowski P, Pentimalli TM, Jüttner R, Glažar P, Uppal K, Bottani E, Brunetti D, Secker C, Zink A, Meierhofer D, Henke MT, Dey M, Ciptasari U, Mlody B, Hahn T, Berruezo-Llacuna M, Karaiskos N, Di Virgilio M, Mayr JA, Wortmann SB, Priller J, Gotthardt M, Jones DP, Mayatepek E, Stenzel W, Diecke S, Kühn R, Wanker EE, Rajewsky N, Schuelke M, Prigione A. Inak G, et al. Among authors: brunetti d. Nat Commun. 2021 Mar 26;12(1):1929. doi: 10.1038/s41467-021-22117-z. Nat Commun. 2021. PMID: 33771987 Free PMC article.
Advances in Mitochondria-Targeted Drug Delivery.
Bottani E, Brunetti D. Bottani E, et al. Among authors: brunetti d. Pharmaceutics. 2023 Aug 5;15(8):2089. doi: 10.3390/pharmaceutics15082089. Pharmaceutics. 2023. PMID: 37631303 Free PMC article.
SURF1 knockout cloned pigs: Early onset of a severe lethal phenotype.
Quadalti C, Brunetti D, Lagutina I, Duchi R, Perota A, Lazzari G, Cerutti R, Di Meo I, Johnson M, Bottani E, Crociara P, Corona C, Grifoni S, Tiranti V, Fernandez-Vizarra E, Robinson AJ, Viscomi C, Casalone C, Zeviani M, Galli C. Quadalti C, et al. Among authors: brunetti d. Biochim Biophys Acta Mol Basis Dis. 2018 Jun;1864(6 Pt A):2131-2142. doi: 10.1016/j.bbadis.2018.03.021. Epub 2018 Mar 28. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 29601977 Free PMC article.
Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids.
Pérez MJ, Ivanyuk D, Panagiotakopoulou V, Di Napoli G, Kalb S, Brunetti D, Al-Shaana R, Kaeser SA, Fraschka SA, Jucker M, Zeviani M, Viscomi C, Deleidi M. Pérez MJ, et al. Among authors: brunetti d. Mol Psychiatry. 2021 Oct;26(10):5733-5750. doi: 10.1038/s41380-020-0807-4. Epub 2020 Jul 7. Mol Psychiatry. 2021. PMID: 32632204 Free PMC article.
63 results