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A Novel N-Substituted Valine Derivative with Unique Peroxisome Proliferator-Activated Receptor γ Binding Properties and Biological Activities.
Peiretti F, Montanari R, Capelli D, Bonardo B, Colson C, Amri EZ, Grimaldi M, Balaguer P, Ito K, Roeder RG, Pochetti G, Brunel JM. Peiretti F, et al. Among authors: brunel jm. J Med Chem. 2020 Nov 12;63(21):13124-13139. doi: 10.1021/acs.jmedchem.0c01555. Epub 2020 Nov 3. J Med Chem. 2020. PMID: 33142057 Free PMC article.
Exploring Selective Inhibition of the First Bromodomain of the Human Bromodomain and Extra-terminal Domain (BET) Proteins.
Raux B, Voitovich Y, Derviaux C, Lugari A, Rebuffet E, Milhas S, Priet S, Roux T, Trinquet E, Guillemot JC, Knapp S, Brunel JM, Fedorov AY, Collette Y, Roche P, Betzi S, Combes S, Morelli X. Raux B, et al. Among authors: brunel jm. J Med Chem. 2016 Feb 25;59(4):1634-41. doi: 10.1021/acs.jmedchem.5b01708. Epub 2016 Jan 6. J Med Chem. 2016. PMID: 26735842
The beta secretase BACE1 regulates the expression of insulin receptor in the liver.
Meakin PJ, Mezzapesa A, Benabou E, Haas ME, Bonardo B, Grino M, Brunel JM, Desbois-Mouthon C, Biddinger SB, Govers R, Ashford MLJ, Peiretti F. Meakin PJ, et al. Among authors: brunel jm. Nat Commun. 2018 Apr 3;9(1):1306. doi: 10.1038/s41467-018-03755-2. Nat Commun. 2018. PMID: 29610518 Free PMC article.
Antibiotic Adjuvants: Make Antibiotics Great Again!
Douafer H, Andrieu V, Phanstiel O 4th, Brunel JM. Douafer H, et al. Among authors: brunel jm. J Med Chem. 2019 Oct 10;62(19):8665-8681. doi: 10.1021/acs.jmedchem.8b01781. Epub 2019 May 16. J Med Chem. 2019. PMID: 31063379 Review.
Artificial Intelligence: The Future for Organic Chemistry?
Peiretti F, Brunel JM. Peiretti F, et al. Among authors: brunel jm. ACS Omega. 2018 Oct 16;3(10):13263-13266. doi: 10.1021/acsomega.8b01773. eCollection 2018 Oct 31. ACS Omega. 2018. PMID: 31458044 Free PMC article. Review.
138 results