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Glutathione increase by the n-butanoyl glutathione derivative (GSH-C4) inhibits viral replication and induces a predominant Th1 immune profile in old mice infected with influenza virus.
Amatore D, Celestino I, Brundu S, Galluzzi L, Coluccio P, Checconi P, Magnani M, Palamara AT, Fraternale A, Nencioni L. Amatore D, et al. Among authors: brundu s. FASEB Bioadv. 2019 Mar 13;1(5):296-305. doi: 10.1096/fba.2018-00066. eCollection 2019 May. FASEB Bioadv. 2019. PMID: 32123833 Free PMC article.
Glutathione Depletion Is Linked with Th2 Polarization in Mice with a Retrovirus-Induced Immunodeficiency Syndrome, Murine AIDS: Role of Proglutathione Molecules as Immunotherapeutics.
Brundu S, Palma L, Picceri GG, Ligi D, Orlandi C, Galluzzi L, Chiarantini L, Casabianca A, Schiavano GF, Santi M, Mannello F, Green K, Smietana M, Magnani M, Fraternale A. Brundu S, et al. J Virol. 2016 Jul 27;90(16):7118-7130. doi: 10.1128/JVI.00603-16. Print 2016 Aug 15. J Virol. 2016. PMID: 27226373 Free PMC article.
HIV Protease Inhibitors Block HPV16-Induced Murine Cervical Carcinoma and Promote Vessel Normalization in Association with MMP-9 Inhibition and TIMP-3 Induction.
Qiu Y, Maione F, Capano S, Meda C, Picconi O, Brundu S, Pisacane A, Sapino A, Palladino C, Barillari G, Monini P, Bussolino F, Ensoli B, Sgadari C, Giraudo E. Qiu Y, et al. Among authors: brundu s. Mol Cancer Ther. 2020 Dec;19(12):2476-2489. doi: 10.1158/1535-7163.MCT-20-0055. Epub 2020 Oct 20. Mol Cancer Ther. 2020. PMID: 33082275
Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability.
Gioelli N, Neilson LJ, Wei N, Villari G, Chen W, Kuhle B, Ehling M, Maione F, Willox S, Brundu S, Avanzato D, Koulouras G, Mazzone M, Giraudo E, Yang XL, Valdembri D, Zanivan S, Serini G. Gioelli N, et al. Among authors: brundu s. Nat Commun. 2022 Jul 20;13(1):4188. doi: 10.1038/s41467-022-31904-1. Nat Commun. 2022. PMID: 35858913 Free PMC article.
Nucleolin Therapeutic Targeting Decreases Pancreatic Cancer Immunosuppression.
Ponzo M, Debesset A, Cossutta M, Chalabi-Dchar M, Houppe C, Pilon C, Nicolas-Boluda A, Meunier S, Raineri F, Thiolat A, Nicolle R, Maione F, Brundu S, Cojocaru CF, Bouvet P, Bousquet C, Gazeau F, Tournigand C, Courty J, Giraudo E, Cohen JL, Cascone I. Ponzo M, et al. Among authors: brundu s. Cancers (Basel). 2022 Aug 31;14(17):4265. doi: 10.3390/cancers14174265. Cancers (Basel). 2022. PMID: 36077801 Free PMC article.
Mutated axon guidance gene PLXNB2 sustains growth and invasiveness of stem cells isolated from cancers of unknown primary.
Brundu S, Napolitano V, Franzolin G, Lo Cascio E, Mastrantonio R, Sardo G, Cascardi E, Verginelli F, Sarnataro S, Gambardella G, Pisacane A, Arcovito A, Boccaccio C, Comoglio PM, Giraudo E, Tamagnone L. Brundu S, et al. EMBO Mol Med. 2023 Mar 8;15(3):e16104. doi: 10.15252/emmm.202216104. Epub 2023 Feb 1. EMBO Mol Med. 2023. PMID: 36722641 Free PMC article.
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