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A Cre-driven allele-conditioning line to interrogate CD4+ conventional T cells.
Andrews LP, Vignali KM, Szymczak-Workman AL, Burton AR, Brunazzi EA, Ngiow SF, Harusato A, Sharpe AH, Wherry EJ, Taniuchi I, Workman CJ, Vignali DAA. Andrews LP, et al. Among authors: brunazzi ea. Immunity. 2021 Oct 12;54(10):2209-2217.e6. doi: 10.1016/j.immuni.2021.08.029. Epub 2021 Sep 21. Immunity. 2021. PMID: 34551314 Free article.
Regulatory T Cell-Derived TRAIL Is Not Required for Peripheral Tolerance.
Dadey RE, Grebinoski S, Zhang Q, Brunazzi EA, Burton A, Workman CJ, Vignali DAA. Dadey RE, et al. Among authors: brunazzi ea. Immunohorizons. 2021 Jan 22;5(1):48-58. doi: 10.4049/immunohorizons.2000098. Immunohorizons. 2021. PMID: 33483333 Free PMC article.
Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ.
Liu C, Chikina M, Deshpande R, Menk AV, Wang T, Tabib T, Brunazzi EA, Vignali KM, Sun M, Stolz DB, Lafyatis RA, Chen W, Delgoffe GM, Workman CJ, Wendell SG, Vignali DAA. Liu C, et al. Among authors: brunazzi ea. Immunity. 2019 Aug 20;51(2):381-397.e6. doi: 10.1016/j.immuni.2019.06.017. Epub 2019 Jul 23. Immunity. 2019. PMID: 31350177 Free PMC article.
Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity.
Overacre-Delgoffe AE, Chikina M, Dadey RE, Yano H, Brunazzi EA, Shayan G, Horne W, Moskovitz JM, Kolls JK, Sander C, Shuai Y, Normolle DP, Kirkwood JM, Ferris RL, Delgoffe GM, Bruno TC, Workman CJ, Vignali DAA. Overacre-Delgoffe AE, et al. Among authors: brunazzi ea. Cell. 2017 Jun 1;169(6):1130-1141.e11. doi: 10.1016/j.cell.2017.05.005. Epub 2017 May 25. Cell. 2017. PMID: 28552348 Free PMC article.