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Malignant pleural mesothelioma co-opts BCL-XL and autophagy to escape apoptosis.
Xu D, Liang SQ, Yang Z, Yang H, Bruggmann R, Oberhaensli S, Berezowska S, Marti TM, Hall SRR, Dorn P, Kocher GJ, Schmid RA, Peng RW. Xu D, et al. Among authors: bruggmann r. Cell Death Dis. 2021 Apr 15;12(4):406. doi: 10.1038/s41419-021-03668-x. Cell Death Dis. 2021. PMID: 33859162 Free PMC article.
Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma.
Xu D, Liang SQ, Yang H, Lüthi U, Riether C, Berezowska S, Marti TM, Hall SRR, Bruggmann R, Kocher GJ, Schmid RA, Peng RW. Xu D, et al. Among authors: bruggmann r. Br J Cancer. 2018 Jul;119(1):65-75. doi: 10.1038/s41416-018-0145-3. Epub 2018 Jun 20. Br J Cancer. 2018. PMID: 29921948 Free PMC article.
Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549.
Tièche CC, Gao Y, Bührer ED, Hobi N, Berezowska SA, Wyler K, Froment L, Weis S, Peng RW, Bruggmann R, Schär P, Amrein MA, Hall SRR, Dorn P, Kocher G, Riether C, Ochsenbein A, Schmid RA, Marti TM. Tièche CC, et al. Among authors: bruggmann r. Neoplasia. 2019 Feb;21(2):185-196. doi: 10.1016/j.neo.2018.09.008. Epub 2018 Dec 27. Neoplasia. 2019. PMID: 30591423 Free PMC article.
Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage.
Deng H, Gao Y, Trappetti V, Hertig D, Karatkevich D, Losmanova T, Urzi C, Ge H, Geest GA, Bruggmann R, Djonov V, Nuoffer JM, Vermathen P, Zamboni N, Riether C, Ochsenbein A, Peng RW, Kocher GJ, Schmid RA, Dorn P, Marti TM. Deng H, et al. Among authors: bruggmann r. Cell Mol Life Sci. 2022 Jul 25;79(8):445. doi: 10.1007/s00018-022-04453-5. Cell Mol Life Sci. 2022. PMID: 35877003 Free PMC article.
Integrated longitudinal analysis of adult grade 4 diffuse gliomas with long-term relapse interval revealed upregulation of TGF-β signaling in recurrent tumors.
Kashani E, Schnidrig D, Gheinani AH, Ninck MS, Zens P, Maragkou T, Baumgartner U, Schucht P, Rätsch G, Rubin MA; SOCIBP consortium; Berezowska S, Ng CKY, Vassella E. Kashani E, et al. Neuro Oncol. 2023 Apr 6;25(4):662-673. doi: 10.1093/neuonc/noac220. Neuro Oncol. 2023. PMID: 36124685 Free PMC article.
The wheat powdery mildew genome shows the unique evolution of an obligate biotroph.
Wicker T, Oberhaensli S, Parlange F, Buchmann JP, Shatalina M, Roffler S, Ben-David R, Doležel J, Šimková H, Schulze-Lefert P, Spanu PD, Bruggmann R, Amselem J, Quesneville H, Ver Loren van Themaat E, Paape T, Shimizu KK, Keller B. Wicker T, et al. Among authors: bruggmann r. Nat Genet. 2013 Sep;45(9):1092-6. doi: 10.1038/ng.2704. Epub 2013 Jul 14. Nat Genet. 2013. PMID: 23852167 Free article.
129 results