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Class IIa HDACs inhibit cell death pathways and protect muscle integrity in response to lipotoxicity.
Martin SD, Connor T, Sanigorski A, McEwen KA, Henstridge DC, Nijagal B, De Souza D, Tull DL, Meikle PJ, Kowalski GM, Bruce CR, Gregorevic P, Febbraio MA, Collier FM, Walder KR, McGee SL. Martin SD, et al. Among authors: bruce cr. Cell Death Dis. 2023 Dec 1;14(12):787. doi: 10.1038/s41419-023-06319-5. Cell Death Dis. 2023. PMID: 38040704 Free PMC article.
It's what you do with the fat that matters!
Bruce CR, Febbraio MA. Bruce CR, et al. Nat Med. 2007 Oct;13(10):1137-8. doi: 10.1038/nm1007-1137. Nat Med. 2007. PMID: 17917654 No abstract available.
HSP72 protects against obesity-induced insulin resistance.
Chung J, Nguyen AK, Henstridge DC, Holmes AG, Chan MH, Mesa JL, Lancaster GI, Southgate RJ, Bruce CR, Duffy SJ, Horvath I, Mestril R, Watt MJ, Hooper PL, Kingwell BA, Vigh L, Hevener A, Febbraio MA. Chung J, et al. Among authors: bruce cr. Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1739-44. doi: 10.1073/pnas.0705799105. Epub 2008 Jan 25. Proc Natl Acad Sci U S A. 2008. PMID: 18223156 Free PMC article.
Brain-derived neurotrophic factor is produced by skeletal muscle cells in response to contraction and enhances fat oxidation via activation of AMP-activated protein kinase.
Matthews VB, Aström MB, Chan MH, Bruce CR, Krabbe KS, Prelovsek O, Akerström T, Yfanti C, Broholm C, Mortensen OH, Penkowa M, Hojman P, Zankari A, Watt MJ, Bruunsgaard H, Pedersen BK, Febbraio MA. Matthews VB, et al. Among authors: bruce cr. Diabetologia. 2009 Jul;52(7):1409-18. doi: 10.1007/s00125-009-1364-1. Epub 2009 Apr 22. Diabetologia. 2009. PMID: 19387610
177 results