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Page 1
Development and characterization of NILK-2301, a novel CEACAM5xCD3 κλ bispecific antibody for immunotherapy of CEACAM5-expressing cancers.
J Hematol Oncol. 2023 Dec 12;16(1):117. doi: 10.1186/s13045-023-01516-3.
J Hematol Oncol. 2023.
PMID: 38087365
Free PMC article.
Targeting a membrane-proximal epitope on mesothelin increases the tumoricidal activity of a bispecific antibody blocking CD47 on mesothelin-positive tumors.
Hatterer E, Chauchet X, Richard F, Barba L, Moine V, Chatel L, Broyer L, Pontini G, Bautzova T, Juan F, Calloud S, Bosson N, Charreton M, Masternak K, Buatois V, Shang L.
Hatterer E, et al. Among authors: broyer l.
MAbs. 2020 Jan-Dec;12(1):1739408. doi: 10.1080/19420862.2020.1739408.
MAbs. 2020.
PMID: 32191151
Free PMC article.
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Preclinical Development of a Bispecific Antibody that Safely and Effectively Targets CD19 and CD47 for the Treatment of B-Cell Lymphoma and Leukemia.
Buatois V, Johnson Z, Salgado-Pires S, Papaioannou A, Hatterer E, Chauchet X, Richard F, Barba L, Daubeuf B, Cons L, Broyer L, D'Asaro M, Matthes T, LeGallou S, Fest T, Tarte K, Clarke Hinojosa RK, Genescà Ferrer E, Ribera JM, Dey A, Bailey K, Fielding AK, Eissenberg L, Ritchey J, Rettig M, DiPersio JF, Kosco-Vilbois MH, Masternak K, Fischer N, Shang L, Ferlin WG.
Buatois V, et al. Among authors: broyer l.
Mol Cancer Ther. 2018 Aug;17(8):1739-1751. doi: 10.1158/1535-7163.MCT-17-1095. Epub 2018 May 9.
Mol Cancer Ther. 2018.
PMID: 29743205
Free PMC article.
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Tumor-Directed Blockade of CD47 with Bispecific Antibodies Induces Adaptive Antitumor Immunity.
Dheilly E, Majocchi S, Moine V, Didelot G, Broyer L, Calloud S, Malinge P, Chatel L, Ferlin WG, Kosco-Vilbois MH, Fischer N, Masternak K.
Dheilly E, et al. Among authors: broyer l.
Antibodies (Basel). 2018 Jan 3;7(1):3. doi: 10.3390/antib7010003.
Antibodies (Basel). 2018.
PMID: 31544856
Free PMC article.
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Selective Blockade of the Ubiquitous Checkpoint Receptor CD47 Is Enabled by Dual-Targeting Bispecific Antibodies.
Dheilly E, Moine V, Broyer L, Salgado-Pires S, Johnson Z, Papaioannou A, Cons L, Calloud S, Majocchi S, Nelson R, Rousseau F, Ferlin W, Kosco-Vilbois M, Fischer N, Masternak K.
Dheilly E, et al. Among authors: broyer l.
Mol Ther. 2017 Feb 1;25(2):523-533. doi: 10.1016/j.ymthe.2016.11.006.
Mol Ther. 2017.
PMID: 28153099
Free PMC article.
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Exploiting light chains for the scalable generation and platform purification of native human bispecific IgG.
Fischer N, Elson G, Magistrelli G, Dheilly E, Fouque N, Laurendon A, Gueneau F, Ravn U, Depoisier JF, Moine V, Raimondi S, Malinge P, Di Grazia L, Rousseau F, Poitevin Y, Calloud S, Cayatte PA, Alcoz M, Pontini G, Fagète S, Broyer L, Corbier M, Schrag D, Didelot G, Bosson N, Costes N, Cons L, Buatois V, Johnson Z, Ferlin W, Masternak K, Kosco-Vilbois M.
Fischer N, et al. Among authors: broyer l.
Nat Commun. 2015 Feb 12;6:6113. doi: 10.1038/ncomms7113.
Nat Commun. 2015.
PMID: 25672245
Free PMC article.
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Evaluation of complement-dependent cytotoxicity using ATP measurement and C1q/C4b binding.
Broyer L, Goetsch L, Broussas M.
Broyer L, et al.
Methods Mol Biol. 2013;988:319-29. doi: 10.1007/978-1-62703-327-5_20.
Methods Mol Biol. 2013.
PMID: 23475729
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Evaluation of antibody-dependent cell cytotoxicity using lactate dehydrogenase (LDH) measurement.
Broussas M, Broyer L, Goetsch L.
Broussas M, et al. Among authors: broyer l.
Methods Mol Biol. 2013;988:305-17. doi: 10.1007/978-1-62703-327-5_19.
Methods Mol Biol. 2013.
PMID: 23475728
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