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Purine synthesis suppression reduces the development and progression of pulmonary hypertension in rodent models.
Ma Q, Yang Q, Xu J, Sellers HG, Brown ZL, Liu Z, Bordan Z, Shi X, Zhao D, Cai Y, Pareek V, Zhang C, Wu G, Dong Z, Verin AD, Gan L, Du Q, Benkovic SJ, Xu S, Asara JM, Ben-Sahra I, Barman S, Su Y, Fulton DJR, Huo Y. Ma Q, et al. Among authors: brown zl. Eur Heart J. 2023 Apr 7;44(14):1265-1279. doi: 10.1093/eurheartj/ehad044. Eur Heart J. 2023. PMID: 36721994 Free PMC article.
PDZ-Binding Kinase, a Novel Regulator of Vascular Remodeling in Pulmonary Arterial Hypertension.
Bordan Z, Batori R, Haigh S, Li X, Meadows ML, Brown ZL, West MA, Dong K, Han W, Su Y, Ma Q, Huo Y, Zhou J, Abdelbary M, Sullivan J, Weintraub NL, Stepp DW, Chen F, Barman SA, Fulton DJR. Bordan Z, et al. Among authors: brown zl. Circulation. 2024 Apr 29. doi: 10.1161/CIRCULATIONAHA.123.067095. Online ahead of print. Circulation. 2024. PMID: 38682326
Early Endothelial Dysfunction in a Novel Model of Sustained Hyperphagia and Obesity in Mice Using a Brain Targeting Adeno-Associated Virus.
Sellers HG, Padgett CA, Mintz JD, Speese AC, Brown ZL, Haigh S, Sword J, Rosewater CL, Shivers MA, Barris CT, Kirov SA, Weintraub NL, Belin de Chantemele EJ, Stepp DW, Fulton DJR. Sellers HG, et al. Among authors: brown zl. Arterioscler Thromb Vasc Biol. 2023 Aug;43(8):1592-1594. doi: 10.1161/ATVBAHA.122.318658. Epub 2023 May 25. Arterioscler Thromb Vasc Biol. 2023. PMID: 37226731 No abstract available.