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Efficacy and safety of ciclosporin versus methotrexate in the treatment of severe atopic dermatitis in children and young people (TREAT): a multicentre parallel group assessor-blinded clinical trial.
Flohr C, Rosala-Hallas A, Jones AP, Beattie P, Baron S, Browne F, Brown SJ, Gach JE, Greenblatt D, Hearn R, Hilger E, Esdaile B, Cork MJ, Howard E, Lovgren ML, August S, Ashoor F, Williamson PR, McPherson T, O'Kane D, Ravenscroft J, Shaw L, Sinha MD, Spowart C, Taams LS, Thomas BR, Wan M, Sach TH, Irvine AD; TREAT Trial Investigators. Flohr C, et al. Among authors: brown sj. Br J Dermatol. 2023 Nov 16;189(6):674-684. doi: 10.1093/bjd/ljad281. Br J Dermatol. 2023. PMID: 37722926 Free article. Clinical Trial.
Atopic eczema and the filaggrin story.
Brown SJ, Irvine AD. Brown SJ, et al. Semin Cutan Med Surg. 2008 Jun;27(2):128-37. doi: 10.1016/j.sder.2008.04.001. Semin Cutan Med Surg. 2008. PMID: 18620134 Review.
Wide spectrum of filaggrin-null mutations in atopic dermatitis highlights differences between Singaporean Chinese and European populations.
Chen H, Common JE, Haines RL, Balakrishnan A, Brown SJ, Goh CS, Cordell HJ, Sandilands A, Campbell LE, Kroboth K, Irvine AD, Goh DL, Tang MB, van Bever HP, Giam YC, McLean WH, Lane EB. Chen H, et al. Among authors: brown sj. Br J Dermatol. 2011 Jul;165(1):106-14. doi: 10.1111/j.1365-2133.2011.10331.x. Br J Dermatol. 2011. PMID: 21428977
Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects.
Saunders SP, Goh CS, Brown SJ, Palmer CN, Porter RM, Cole C, Campbell LE, Gierlinski M, Barton GJ, Schneider G, Balmain A, Prescott AR, Weidinger S, Baurecht H, Kabesch M, Gieger C, Lee YA, Tavendale R, Mukhopadhyay S, Turner SW, Madhok VB, Sullivan FM, Relton C, Burn J, Meggitt S, Smith CH, Allen MA, Barker JN, Reynolds NJ, Cordell HJ, Irvine AD, McLean WH, Sandilands A, Fallon PG. Saunders SP, et al. Among authors: brown sj. J Allergy Clin Immunol. 2013 Nov;132(5):1121-9. doi: 10.1016/j.jaci.2013.08.046. Epub 2013 Sep 29. J Allergy Clin Immunol. 2013. PMID: 24084074 Free PMC article.
South African amaXhosa patients with atopic dermatitis have decreased levels of filaggrin breakdown products but no loss-of-function mutations in filaggrin.
Thawer-Esmail F, Jakasa I, Todd G, Wen Y, Brown SJ, Kroboth K, Campbell LE, O'Regan GM, McLean WH, Irvine AD, Kezic S, Sandilands A. Thawer-Esmail F, et al. Among authors: brown sj. J Allergy Clin Immunol. 2014 Jan;133(1):280-2.e1-2. doi: 10.1016/j.jaci.2013.09.053. J Allergy Clin Immunol. 2014. PMID: 24369804 Free PMC article. No abstract available.
A multi-centre, parallel group superiority trial of silk therapeutic clothing compared to standard care for the management of eczema in children (CLOTHES Trial): study protocol for a randomised controlled trial.
Harrison EF, Haines RH, Cowdell F, Sach TH, Dean T, Pollock I, Burrows NP, Buckley H, Batchelor J, Williams HC, Lawton S, Brown SJ, Bradshaw LE, Ahmed A, Montgomery AA, Mitchell EJ, Thomas KS. Harrison EF, et al. Among authors: brown sj. Trials. 2015 Sep 2;16:390. doi: 10.1186/s13063-015-0921-9. Trials. 2015. PMID: 26329718 Free PMC article. Clinical Trial.
813 results