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Discovery and optimization of spirocyclic lactams that inhibit acyl-ACP thioesterase.
Asmus E, Barber DM, Bojack G, Bollenbach-Wahl B, Brown RW, Döller U, Freigang J, Gatzweiler E, Getachew R, Heinemann I, Hohmann S, Ko KY, Laber B, Lange G, Mattison RL, Minn K, Müller T, Petry T, Reingruber AM, Schmutzler D, Svejda A, Frackenpohl J. Asmus E, et al. Among authors: brown rw. Pest Manag Sci. 2024 Feb 9. doi: 10.1002/ps.8015. Online ahead of print. Pest Manag Sci. 2024. PMID: 38334233
A Predictive Machine Learning Tool for Asthma Exacerbations: Results from a 12-Week, Open-Label Study Using an Electronic Multi-Dose Dry Powder Inhaler with Integrated Sensors.
Lugogo NL, DePietro M, Reich M, Merchant R, Chrystyn H, Pleasants R, Granovsky L, Li T, Hill T, Brown RW, Safioti G. Lugogo NL, et al. Among authors: brown rw. J Asthma Allergy. 2022 Nov 11;15:1623-1637. doi: 10.2147/JAA.S377631. eCollection 2022. J Asthma Allergy. 2022. PMID: 36387836 Free PMC article.
Trypanosoma brucei Acyl-Protein Thioesterase-like (TbAPT-L) Is a Lipase with Esterase Activity for Short and Medium-Chain Fatty Acids but Has No Depalmitoylation Activity.
Brown RWB, Sharma AI, Villanueva MR, Li X, Onguka O, Zilbermintz L, Nguyen H, Falk BA, Olson CL, Taylor JM, Epting CL, Kathayat RS, Amara N, Dickinson BC, Bogyo M, Engman DM. Brown RWB, et al. Pathogens. 2022 Oct 27;11(11):1245. doi: 10.3390/pathogens11111245. Pathogens. 2022. PMID: 36364996 Free PMC article.
369 results