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617 results

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Page 1
Oncogenic CDK13 mutations impede nuclear RNA surveillance.
Insco ML, Abraham BJ, Dubbury SJ, Kaltheuner IH, Dust S, Wu C, Chen KY, Liu D, Bellaousov S, Cox AM, Martin BJE, Zhang T, Ludwig CG, Fabo T, Modhurima R, Esgdaille DE, Henriques T, Brown KM, Chanock SJ, Geyer M, Adelman K, Sharp PA, Young RA, Boutz PL, Zon LI. Insco ML, et al. Among authors: brown km. Science. 2023 Apr 21;380(6642):eabn7625. doi: 10.1126/science.abn7625. Epub 2023 Apr 21. Science. 2023. PMID: 37079685 Free PMC article.
The genomic landscape of cutaneous melanoma.
Zhang T, Dutton-Regester K, Brown KM, Hayward NK. Zhang T, et al. Among authors: brown km. Pigment Cell Melanoma Res. 2016 May;29(3):266-83. doi: 10.1111/pcmr.12459. Epub 2016 Mar 4. Pigment Cell Melanoma Res. 2016. PMID: 26833684 Review.
Loci associated with skin pigmentation identified in African populations.
Crawford NG, Kelly DE, Hansen MEB, Beltrame MH, Fan S, Bowman SL, Jewett E, Ranciaro A, Thompson S, Lo Y, Pfeifer SP, Jensen JD, Campbell MC, Beggs W, Hormozdiari F, Mpoloka SW, Mokone GG, Nyambo T, Meskel DW, Belay G, Haut J; NISC Comparative Sequencing Program; Rothschild H, Zon L, Zhou Y, Kovacs MA, Xu M, Zhang T, Bishop K, Sinclair J, Rivas C, Elliot E, Choi J, Li SA, Hicks B, Burgess S, Abnet C, Watkins-Chow DE, Oceana E, Song YS, Eskin E, Brown KM, Marks MS, Loftus SK, Pavan WJ, Yeager M, Chanock S, Tishkoff SA. Crawford NG, et al. Among authors: brown km. Science. 2017 Nov 17;358(6365):eaan8433. doi: 10.1126/science.aan8433. Epub 2017 Oct 12. Science. 2017. PMID: 29025994 Free PMC article.
Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma.
Choi J, Zhang T, Vu A, Ablain J, Makowski MM, Colli LM, Xu M, Hennessey RC, Yin J, Rothschild H, Gräwe C, Kovacs MA, Funderburk KM, Brossard M, Taylor J, Pasaniuc B, Chari R, Chanock SJ, Hoggart CJ, Demenais F, Barrett JH, Law MH, Iles MM, Yu K, Vermeulen M, Zon LI, Brown KM. Choi J, et al. Among authors: brown km. Nat Commun. 2020 Jun 1;11(1):2718. doi: 10.1038/s41467-020-16590-1. Nat Commun. 2020. PMID: 32483191 Free PMC article.
Integrated Analysis of Coexpression and Exome Sequencing to Prioritize Susceptibility Genes for Familial Cutaneous Melanoma.
Yepes S, Tucker MA, Koka H, Xiao Y, Zhang T, Jones K, Vogt A, Burdette L, Luo W, Zhu B, Hutchinson A, Yeager M, Hicks B, Brown KM, Freedman ND, Chanock SJ, Goldstein AM, Yang XR. Yepes S, et al. Among authors: brown km. J Invest Dermatol. 2022 Sep;142(9):2464-2475.e5. doi: 10.1016/j.jid.2022.01.029. Epub 2022 Feb 16. J Invest Dermatol. 2022. PMID: 35181301 Free PMC article.
Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation.
Kim H, Frederick DT, Levesque MP, Cooper ZA, Feng Y, Krepler C, Brill L, Samuels Y, Hayward NK, Perlina A, Piris A, Zhang T, Halaban R, Herlyn MM, Brown KM, Wargo JA, Dummer R, Flaherty KT, Ronai ZA. Kim H, et al. Among authors: brown km. Cell Rep. 2015 Jun 9;11(9):1458-73. doi: 10.1016/j.celrep.2015.04.049. Epub 2015 May 28. Cell Rep. 2015. PMID: 26027934 Free PMC article.
SDHD Promoter Mutations Ablate GABP Transcription Factor Binding in Melanoma.
Zhang T, Xu M, Makowski MM, Lee C, Kovacs M, Fang J, Willems E, Trent JM, Hayward NK, Vermeulen M, Brown KM. Zhang T, et al. Among authors: brown km. Cancer Res. 2017 Apr 1;77(7):1649-1661. doi: 10.1158/0008-5472.CAN-16-0919. Epub 2017 Jan 20. Cancer Res. 2017. PMID: 28108517 Free PMC article.
Characterising cis-regulatory variation in the transcriptome of histologically normal and tumour-derived pancreatic tissues.
Zhang M, Lykke-Andersen S, Zhu B, Xiao W, Hoskins JW, Zhang X, Rost LM, Collins I, Bunt MV, Jia J, Parikh H, Zhang T, Song L, Jermusyk A, Chung CC, Zhu B, Zhou W, Matters GL, Kurtz RC, Yeager M, Jensen TH, Brown KM, Ongen H, Bamlet WR, Murray BA, McCarthy MI, Chanock SJ, Chatterjee N, Wolpin BM, Smith JP, Olson SH, Petersen GM, Shi J, Amundadottir L. Zhang M, et al. Among authors: brown km. Gut. 2018 Mar;67(3):521-533. doi: 10.1136/gutjnl-2016-313146. Epub 2017 Jun 20. Gut. 2018. PMID: 28634199 Free PMC article.
617 results