Brown KA - Search Results

1

Obesity promotes breast epithelium DNA damage in women carrying a germline mutation in BRCA1 or BRCA2.

Bhardwaj P, Iyengar NM, Zahid H, Carter KM, Byun DJ, Choi MH, Sun Q, Savenkov O, Louka C, Liu C, Piloco P, Acosta M, Bareja R, Elemento O, Foronda M, Dow LE, Oshchepkova S, Giri DD, Pollak M, Zhou XK, Hopkins BD, Laughney AM, Frey MK, Ellenson LH, Morrow M, Spector JA, Cantley LC, Brown KA. Bhardwaj P, et al. Among authors: brown ka. Sci Transl Med. 2023 Feb 22;15(684):eade1857. doi: 10.1126/scitranslmed.ade1857. Epub 2023 Feb 22. Sci Transl Med. 2023. PMID: 36812344 Free PMC article.

2

Des-acyl ghrelin inhibits the capacity of macrophages to stimulate the expression of aromatase in breast adipose stromal cells.

Au CC, Docanto MM, Zahid H, Raffaelli FM, Ferrero RL, Furness JB, Brown KA. Au CC, et al. Among authors: brown ka. J Steroid Biochem Mol Biol. 2017 Jun;170:49-53. doi: 10.1016/j.jsbmb.2016.07.005. Epub 2016 Jul 14. J Steroid Biochem Mol Biol. 2017. PMID: 27423512

3

Hsp90 and PKM2 Drive the Expression of Aromatase in Li-Fraumeni Syndrome Breast Adipose Stromal Cells.

Subbaramaiah K, Brown KA, Zahid H, Balmus G, Weiss RS, Herbert BS, Dannenberg AJ. Subbaramaiah K, et al. Among authors: brown ka. J Biol Chem. 2016 Jul 29;291(31):16011-23. doi: 10.1074/jbc.M115.698902. Epub 2016 Jun 1. J Biol Chem. 2016. PMID: 27467582 Free PMC article. Retracted.

4

Inflammation, dysregulated metabolism and aromatase in obesity and breast cancer.

Zahid H, Simpson ER, Brown KA. Zahid H, et al. Among authors: brown ka. Curr Opin Pharmacol. 2016 Dec;31:90-96. doi: 10.1016/j.coph.2016.11.003. Epub 2016 Nov 19. Curr Opin Pharmacol. 2016. PMID: 27875786 Review.

5

Metabolic Obesity, Adipose Inflammation and Elevated Breast Aromatase in Women with Normal Body Mass Index.

Iyengar NM, Brown KA, Zhou XK, Gucalp A, Subbaramaiah K, Giri DD, Zahid H, Bhardwaj P, Wendel NK, Falcone DJ, Wang H, Williams S, Pollak M, Morrow M, Hudis CA, Dannenberg AJ. Iyengar NM, et al. Among authors: brown ka. Cancer Prev Res (Phila). 2017 Apr;10(4):235-243. doi: 10.1158/1940-6207.CAPR-16-0314. Epub 2017 Mar 7. Cancer Prev Res (Phila). 2017. PMID: 28270386 Free PMC article.

6

Menopause Is a Determinant of Breast Aromatase Expression and Its Associations With BMI, Inflammation, and Systemic Markers.

Brown KA, Iyengar NM, Zhou XK, Gucalp A, Subbaramaiah K, Wang H, Giri DD, Morrow M, Falcone DJ, Wendel NK, Winston LA, Pollak M, Dierickx A, Hudis CA, Dannenberg AJ. Brown KA, et al. J Clin Endocrinol Metab. 2017 May 1;102(5):1692-1701. doi: 10.1210/jc.2016-3606. J Clin Endocrinol Metab. 2017. PMID: 28323914 Free PMC article.

7

Leptin regulation of the p53-HIF1α/PKM2-aromatase axis in breast adipose stromal cells: a novel mechanism for the obesity-breast cancer link.

Zahid H, Subbaramaiah K, Iyengar NM, Zhou XK, Chen IC, Bhardwaj P, Gucalp A, Morrow M, Hudis CA, Dannenberg AJ, Brown KA. Zahid H, et al. Among authors: brown ka. Int J Obes (Lond). 2018 Apr;42(4):711-720. doi: 10.1038/ijo.2017.273. Epub 2017 Nov 6. Int J Obes (Lond). 2018. PMID: 29104286 Free PMC article.

8

Estrogens and breast cancer: Mechanisms involved in obesity-related development, growth and progression.

Bhardwaj P, Au CC, Benito-Martin A, Ladumor H, Oshchepkova S, Moges R, Brown KA. Bhardwaj P, et al. Among authors: brown ka. J Steroid Biochem Mol Biol. 2019 May;189:161-170. doi: 10.1016/j.jsbmb.2019.03.002. Epub 2019 Mar 6. J Steroid Biochem Mol Biol. 2019. PMID: 30851382 Free PMC article. Review.

9

Tissue Engineering Models for the Study of Breast Neoplastic Disease and the Tumor Microenvironment.

Premaratne ID, Toyoda Y, Celie KB, Brown KA, Spector JA. Premaratne ID, et al. Among authors: brown ka. Tissue Eng Part B Rev. 2020 Oct;26(5):423-442. doi: 10.1089/ten.TEB.2019.0347. Epub 2020 Apr 13. Tissue Eng Part B Rev. 2020. PMID: 32106785 Review.

10

Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531.

Au CC, Furness JB, Britt K, Oshchepkova S, Ladumor H, Soo KY, Callaghan B, Gerard C, Inghirami G, Mittal V, Wang Y, Huang XY, Spector JA, Andreopoulou E, Zumbo P, Betel D, Dow L, Brown KA. Au CC, et al. Among authors: brown ka. Elife. 2020 Jul 15;9:e56913. doi: 10.7554/eLife.56913. Elife. 2020. PMID: 32667883 Free PMC article.

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