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SPANX Control of Lamin A/C Modulates Nuclear Architecture and Promotes Melanoma Growth.
Lazar I, Fabre B, Feng Y, Khateb A, Turko P, Martinez Gomez JM, Frederick DT, Levesque MP, Feld L, Zhang G, Zhang T, James B, Shklover J, Avitan-Hersh E, Livneh I, Scortegagna M, Brown K, Larsson O, Topisirovic I, Wolfenson H, Herlyn M, Flaherty K, Dummer R, Ronai ZA. Lazar I, et al. Among authors: brown k. Mol Cancer Res. 2020 Oct;18(10):1560-1573. doi: 10.1158/1541-7786.MCR-20-0291. Epub 2020 Jun 22. Mol Cancer Res. 2020. PMID: 32571981 Free PMC article.
Regulation of eIF2α by RNF4 Promotes Melanoma Tumorigenesis and Therapy Resistance.
Avitan-Hersh E, Feng Y, Oknin Vaisman A, Abu Ahmad Y, Zohar Y, Zhang T, Lee JS, Lazar I, Sheikh Khalil S, Feiler Y, Kluger H, Kahana C, Brown K, Ruppin E, Ronai ZA, Orian A. Avitan-Hersh E, et al. Among authors: brown k. J Invest Dermatol. 2020 Dec;140(12):2466-2477. doi: 10.1016/j.jid.2020.04.008. Epub 2020 Apr 29. J Invest Dermatol. 2020. PMID: 32360601 Free PMC article.
PDK1 and SGK3 Contribute to the Growth of BRAF-Mutant Melanomas and Are Potential Therapeutic Targets.
Scortegagna M, Lau E, Zhang T, Feng Y, Sereduk C, Yin H, De SK, Meeth K, Platt JT, Langdon CG, Halaban R, Pellecchia M, Davies MA, Brown K, Stern DF, Bosenberg M, Ronai ZA. Scortegagna M, et al. Among authors: brown k. Cancer Res. 2015 Apr 1;75(7):1399-412. doi: 10.1158/0008-5472.CAN-14-2785. Epub 2015 Feb 24. Cancer Res. 2015. PMID: 25712345 Free PMC article.
Siah2 control of T-regulatory cells limits anti-tumor immunity.
Scortegagna M, Hockemeyer K, Dolgalev I, Poźniak J, Rambow F, Li Y, Feng Y, Tinoco R, Otero DC, Zhang T, Brown K, Bosenberg M, Bradley LM, Marine JC, Aifantis I, Ronai ZA. Scortegagna M, et al. Among authors: brown k. Nat Commun. 2020 Jan 7;11(1):99. doi: 10.1038/s41467-019-13826-7. Nat Commun. 2020. PMID: 31911617 Free PMC article.
Regulation of S100A8 Stability by RNF5 in Intestinal Epithelial Cells Determines Intestinal Inflammation and Severity of Colitis.
Fujita Y, Khateb A, Li Y, Tinoco R, Zhang T, Bar-Yoseph H, Tam MA, Chowers Y, Sabo E, Gerassy-Vainberg S, Starosvetsky E, James B, Brown K, Shen-Orr SS, Bradley LM, Tessier PA, Ronai ZA. Fujita Y, et al. Among authors: brown k. Cell Rep. 2018 Sep 18;24(12):3296-3311.e6. doi: 10.1016/j.celrep.2018.08.057. Cell Rep. 2018. PMID: 30232010 Free PMC article.
DNA promoter hypermethylation of melanocyte lineage genes determines melanoma phenotype.
Sanna A, Phung B, Mitra S, Lauss M, Choi J, Zhang T, Njauw CN, Cordero E, Harbst K, Rosengren F, Cabrita R, Johansson I, Isaksson K, Ingvar C, Carneiro A, Brown K, Tsao H, Andersson M, Pietras K, Jönsson G. Sanna A, et al. Among authors: brown k. JCI Insight. 2022 Oct 10;7(19):e156577. doi: 10.1172/jci.insight.156577. JCI Insight. 2022. PMID: 36040798 Free PMC article.
Cell-type-specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes.
Zhang T, Choi J, Kovacs MA, Shi J, Xu M; NISC Comparative Sequencing Program; Melanoma Meta-Analysis Consortium; Goldstein AM, Trower AJ, Bishop DT, Iles MM, Duffy DL, MacGregor S, Amundadottir LT, Law MH, Loftus SK, Pavan WJ, Brown KM. Zhang T, et al. Among authors: brown km. Genome Res. 2018 Nov;28(11):1621-1635. doi: 10.1101/gr.233304.117. Epub 2018 Oct 17. Genome Res. 2018. PMID: 30333196 Free PMC article.
8,664 results