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Curcumin Combined with FOLFOX Chemotherapy Is Safe and Tolerable in Patients with Metastatic Colorectal Cancer in a Randomized Phase IIa Trial.
Howells LM, Iwuji COO, Irving GRB, Barber S, Walter H, Sidat Z, Griffin-Teall N, Singh R, Foreman N, Patel SR, Morgan B, Steward WP, Gescher A, Thomas AL, Brown K. Howells LM, et al. Among authors: brown k. J Nutr. 2019 Jul 1;149(7):1133-1139. doi: 10.1093/jn/nxz029. J Nutr. 2019. PMID: 31132111 Free PMC article. Clinical Trial.
Prolonged biologically active colonic tissue levels of curcumin achieved after oral administration--a clinical pilot study including assessment of patient acceptability.
Irving GR, Howells LM, Sale S, Kralj-Hans I, Atkin WS, Clark SK, Britton RG, Jones DJ, Scott EN, Berry DP, Hemingway D, Miller AS, Brown K, Gescher AJ, Steward WP. Irving GR, et al. Among authors: brown k. Cancer Prev Res (Phila). 2013 Feb;6(2):119-28. doi: 10.1158/1940-6207.CAPR-12-0281. Epub 2012 Dec 11. Cancer Prev Res (Phila). 2013. PMID: 23233733 Free PMC article. Clinical Trial.
Curcumin inhibits cancer stem cell phenotypes in ex vivo models of colorectal liver metastases, and is clinically safe and tolerable in combination with FOLFOX chemotherapy.
James MI, Iwuji C, Irving G, Karmokar A, Higgins JA, Griffin-Teal N, Thomas A, Greaves P, Cai H, Patel SR, Morgan B, Dennison A, Metcalfe M, Garcea G, Lloyd DM, Berry DP, Steward WP, Howells LM, Brown K. James MI, et al. Among authors: brown k. Cancer Lett. 2015 Aug 10;364(2):135-41. doi: 10.1016/j.canlet.2015.05.005. Epub 2015 May 12. Cancer Lett. 2015. PMID: 25979230 Free PMC article. Clinical Trial.
Phase I randomized, double-blind pilot study of micronized resveratrol (SRT501) in patients with hepatic metastases--safety, pharmacokinetics, and pharmacodynamics.
Howells LM, Berry DP, Elliott PJ, Jacobson EW, Hoffmann E, Hegarty B, Brown K, Steward WP, Gescher AJ. Howells LM, et al. Among authors: brown k. Cancer Prev Res (Phila). 2011 Sep;4(9):1419-25. doi: 10.1158/1940-6207.CAPR-11-0148. Epub 2011 Jun 16. Cancer Prev Res (Phila). 2011. PMID: 21680702 Free PMC article. Clinical Trial.
Cancer chemoprevention: a rapidly evolving field.
Steward WP, Brown K. Steward WP, et al. Among authors: brown k. Br J Cancer. 2013 Jul 9;109(1):1-7. doi: 10.1038/bjc.2013.280. Epub 2013 Jun 4. Br J Cancer. 2013. PMID: 23736035 Free PMC article. Review.
Pilot study of oral anthocyanins for colorectal cancer chemoprevention.
Thomasset S, Berry DP, Cai H, West K, Marczylo TH, Marsden D, Brown K, Dennison A, Garcea G, Miller A, Hemingway D, Steward WP, Gescher AJ. Thomasset S, et al. Among authors: brown k. Cancer Prev Res (Phila). 2009 Jul;2(7):625-33. doi: 10.1158/1940-6207.CAPR-08-0201. Cancer Prev Res (Phila). 2009. PMID: 19584076
8,668 results