Brown JH - Search Results

1

CaMKIIδC Drives Early Adaptive Ca²⁺ Change and Late Eccentric Cardiac Hypertrophy.

Ljubojevic-Holzer S, Herren AW, Djalinac N, Voglhuber J, Morotti S, Holzer M, Wood BM, Abdellatif M, Matzer I, Sacherer M, Radulovic S, Wallner M, Ivanov M, Wagner S, Sossalla S, von Lewinski D, Pieske B, Brown JH, Sedej S, Bossuyt J, Bers DM. Ljubojevic-Holzer S, et al. Among authors: brown jh. Circ Res. 2020 Oct 9;127(9):1159-1178. doi: 10.1161/CIRCRESAHA.120.316947. Epub 2020 Aug 21. Circ Res. 2020. PMID: 32821022 Free PMC article.

2

The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure.

Zhang T, Maier LS, Dalton ND, Miyamoto S, Ross J Jr, Bers DM, Brown JH. Zhang T, et al. Among authors: brown jh. Circ Res. 2003 May 2;92(8):912-9. doi: 10.1161/01.RES.0000069686.31472.C5. Epub 2003 Apr 3. Circ Res. 2003. PMID: 12676814

3

Increased sarcoplasmic reticulum calcium leak but unaltered contractility by acute CaMKII overexpression in isolated rabbit cardiac myocytes.

Kohlhaas M, Zhang T, Seidler T, Zibrova D, Dybkova N, Steen A, Wagner S, Chen L, Brown JH, Bers DM, Maier LS. Kohlhaas M, et al. Among authors: brown jh. Circ Res. 2006 Feb 3;98(2):235-44. doi: 10.1161/01.RES.0000200739.90811.9f. Epub 2005 Dec 22. Circ Res. 2006. PMID: 16373600

4

Phospholamban ablation rescues sarcoplasmic reticulum Ca(2+) handling but exacerbates cardiac dysfunction in CaMKIIdelta(C) transgenic mice.

Zhang T, Guo T, Mishra S, Dalton ND, Kranias EG, Peterson KL, Bers DM, Brown JH. Zhang T, et al. Among authors: brown jh. Circ Res. 2010 Feb 5;106(2):354-62. doi: 10.1161/CIRCRESAHA.109.207423. Epub 2009 Dec 3. Circ Res. 2010. PMID: 19959778 Free PMC article.

5

Location matters: clarifying the concept of nuclear and cytosolic CaMKII subtypes.

Mishra S, Gray CB, Miyamoto S, Bers DM, Brown JH. Mishra S, et al. Among authors: brown jh. Circ Res. 2011 Dec 9;109(12):1354-62. doi: 10.1161/CIRCRESAHA.111.248401. Epub 2011 Oct 13. Circ Res. 2011. PMID: 21998325 Free PMC article.

6

Epac2 mediates cardiac β1-adrenergic-dependent sarcoplasmic reticulum Ca2+ leak and arrhythmia.

Pereira L, Cheng H, Lao DH, Na L, van Oort RJ, Brown JH, Wehrens XH, Chen J, Bers DM. Pereira L, et al. Among authors: brown jh. Circulation. 2013 Feb 26;127(8):913-22. doi: 10.1161/CIRCULATIONAHA.12.148619. Epub 2013 Jan 30. Circulation. 2013. PMID: 23363625 Free PMC article.

7

Transgenic CaMKIIdeltaC overexpression uniquely alters cardiac myocyte Ca2+ handling: reduced SR Ca2+ load and activated SR Ca2+ release.

Maier LS, Zhang T, Chen L, DeSantiago J, Brown JH, Bers DM. Maier LS, et al. Among authors: brown jh. Circ Res. 2003 May 2;92(8):904-11. doi: 10.1161/01.RES.0000069685.20258.F1. Epub 2003 Apr 3. Circ Res. 2003. PMID: 12676813

8

Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels.

Wagner S, Dybkova N, Rasenack EC, Jacobshagen C, Fabritz L, Kirchhof P, Maier SK, Zhang T, Hasenfuss G, Brown JH, Bers DM, Maier LS. Wagner S, et al. Among authors: brown jh. J Clin Invest. 2006 Dec;116(12):3127-38. doi: 10.1172/JCI26620. Epub 2006 Nov 22. J Clin Invest. 2006. PMID: 17124532 Free PMC article.

9

Overexpression of CaMKIIδc in RyR2R4496C+/- knock-in mice leads to altered intracellular Ca2+ handling and increased mortality.

Dybkova N, Sedej S, Napolitano C, Neef S, Rokita AG, Hünlich M, Brown JH, Kockskämper J, Priori SG, Pieske B, Maier LS. Dybkova N, et al. Among authors: brown jh. J Am Coll Cardiol. 2011 Jan 25;57(4):469-79. doi: 10.1016/j.jacc.2010.08.639. J Am Coll Cardiol. 2011. PMID: 21251589 Free article.

10

CaMKII in myocardial hypertrophy and heart failure.

Anderson ME, Brown JH, Bers DM. Anderson ME, et al. Among authors: brown jh. J Mol Cell Cardiol. 2011 Oct;51(4):468-73. doi: 10.1016/j.yjmcc.2011.01.012. Epub 2011 Jan 27. J Mol Cell Cardiol. 2011. PMID: 21276796 Free PMC article. Review.

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